3-octyl-pyrrolidine-2,5-dione | 16516-97-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯烷类
• 英文名称: 3-octyl-pyrrolidine-2,5-dione
• 英文别名: octyl succinimide；3-Octylpyrrolidine-2,5-dione
• CAS: 16516-97-5
• 化学式: C₁₂H₂₁NO₂
• 分子量: 211.304
• InChiKey: YSDGPGHLNIIOKX-UHFFFAOYSA-N

物化性质

• 熔点：
  83-84 °C(Solv: ethanol (64-17-5))
• 沸点：
  139-142 °C(Press: 2 Torr)
• 密度：
  0.985±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  15
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  46.2
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  辛烯 、 丁二酰亚胺 以48%的产率得到
  参考文献：
  名称：

  OGIBIN YU. N.; BREDERMAN I. V.; ALEJNIKOV N. A.; NIKISHIN G. I., IZV. AN CCCP. CEP. XIM., 1980, HO 1, 195-197

  摘要：

  DOI：

文献信息

• Bleaching and detergent compositions
  申请人：UNILEVER N.V.

  公开号：EP0473229A1

  公开（公告）日：1992-03-04

  Novel peroxyacid bleach precursors are disclosed, having the formula : wherein R is an alkyl, aryl or alkaryl group containing from 1 to 10 carbon atoms, or preferably a quaternary ammonium-substituted alkyl, aryl or alkaryl group containing 1 to 10 carbon atoms; and x is an integer from 2-6. These bleach precursors have the advantage of not containing a leaving group. Bleaching-detergent compositions comprising a peroxide compound bleach and the novel peroxyacid bleach precursors are also disclosed.

  本发明公开了新型过氧酸漂白剂前体，其化学式为......： 其中 R 是含有 1 至 10 个碳原子的烷基、芳基或烷芳基，或最好是含有 1 至 10 个碳原子的季铵取代的烷基、芳基或烷芳基；x 是 2 至 6 的整数。这些漂白剂前体的优点是不含离去基团。此外，还公开了包含过氧化物化合物漂白剂和新型过氧酸漂白剂前体的漂白洗涤剂组合物。
• Humanized anti-Tn-MUC1 antibodies and their conjugates
  申请人：ADC THERAPEUTICS S.A.

  公开号：US10017580B2

  公开（公告）日：2018-07-10

  Humanized anti-Tn-MUC1 antibodies and conjugates thereof. Conjugates comprising pyrrolobenzodiazepines (PBDs) having a labile protecting group in the form of a linker to the antibody are described.

  人源化抗 Tn-MUC1 抗体及其共轭物。本研究描述了由吡咯并二氮杂卓（PBD）组成的共轭物，该共轭物具有以连接体形式与抗体连接的易变保护基团。
• Lubricant compositions
  申请人：ETHYL PETROLEUM ADDITIVES, INC.

  公开号：EP0448207B1

  公开（公告）日：1993-12-15
• POWER TRANSMISSION FLUID WITH ENHANCED FRICTION CHARACTERISTICS
  申请人：Henly Timothy J.

  公开号：US20070293406A1

  公开（公告）日：2007-12-20

  A power transmission fluid composition, a power transmission containing the fluid, a method of operating a power transmission with the fluid and method of improving friction durability for a power transmission fluid. The power transmission fluid includes (a) a base oil and (b) an additive composition having therein (i) at least one ashless dispersant; (ii) a metal detergent providing greater than about 100 ppm metal in the power transmission fluid composition; (iii) a friction modifying amount of an imidazoline; (iv) a succinimide friction modifier; and (v) a non-hydroxy tertiary amine friction modifier other than (iii).
• HUMANIZED ANTI-TN-MUC1 ANTIBODIES AND THEIR CONJUGATES
  申请人：ADC THERAPEUTICS S.A.

  公开号：US20170267778A1

  公开（公告）日：2017-09-21

  Humanized anti-Tn-MUC1 antibodies and conjugates thereof. Conjugates comprising pyrrolobenzodiazepines (PBDs) having a labile protecting group in the form of a linker to the antibody are described.