fluoro(naphthalen-1-yl)(phenyl)silane | 63322-14-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: fluoro(naphthalen-1-yl)(phenyl)silane
• 英文别名: α-Naphthylphenylfluorsilan
• CAS: 63322-14-5
• 化学式: C₁₆H₁₃FSi
• 分子量: 252.363
• InChiKey: VVVHXLFABNPBST-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.65
• 重原子数：
  18.0
• 可旋转键数：
  2.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  0.0
• 氢给体数：
  0.0
• 氢受体数：
  0.0

反应信息

• 作为反应物：
  描述：

  2-苯基吡啶 、 fluoro(naphthalen-1-yl)(phenyl)silane 在 降冰片烯 、 iridium(I)-(1,5-cyclooctadiene)-acetylacetonate 作用下， 以 甲苯 为溶剂， 反应 24.0h， 以99%的产率得到2-(2-(fluoro(naphthalen-1-yl)(phenyl)silyl)phenyl)pyridine
  参考文献：
  名称：

  Iridium-Catalyzed ortho-Selective C–H Silylation of Aromatic Compounds Directed toward the Synthesis of π-Conjugated Molecules with Lewis Acid–Base Interaction

  摘要：

  We successfully developed an iridium-catalyzed ortho-selective C-H silylation of aromatic compounds. The reaction exhibited a wide substrate scope, and a variety of pi-conjugated molecules were synthesized in good to excellent yields, even in gram scale. Several silyl groups could also be introduced into the products. The experimental results indicated that the regioselectivity could be controlled by a Lewis acid-base interaction between the Lewis acidic silicon atoms of fluorinated hydrosilanes and the Lewis basic nitrogen atoms of aromatic compounds.

  DOI：

  10.1021/acs.orglett.5b00529
• 作为产物：
  描述：

  Phenyl-α-naphthylchlorsilan 、 五氟化锑 以52%的产率得到
  参考文献：
  名称：

  CORRIU R. J. P.; FERNANDEZ J. M.; GUERIN C., J. ORGANOMETAL. CHEM., 1980, 192, NO 3, 347-352

  摘要：

  DOI：