4-chloro-2,3,5,6-tetrafluorophenyl phenyl sulfide | 35779-15-8

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醚类
• 英文名称: 4-chloro-2,3,5,6-tetrafluorophenyl phenyl sulfide
• 英文别名: 1-phenylthio-4-chloro-tetrafluoro-benzene；1-chloro-2,3,5,6-tetrafluoro-4-phenylsulfanylbenzene
• CAS: 35779-15-8
• 化学式: C₁₂H₅ClF₄S
• 分子量: 292.684
• InChiKey: USKCSIGSPFUUPB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.05
• 重原子数：
  18.0
• 可旋转键数：
  2.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  0.0
• 氢给体数：
  0.0
• 氢受体数：
  1.0

反应信息

• 作为产物：
  描述：

  氯五氟苯 、 Blei-thiophenolat 以99%的产率得到
  参考文献：
  名称：

  PEACH, M. E.;SMITH, K. C., J. FLUOR. CHEM., 1985, 27, N 1, 105-114

  摘要：

  DOI：

文献信息

• The thiolate anion as a nucleophile Part XII. Reactions of Lead(II) Benzenethiolate
  作者：Michael E. Peach、Kevin C. Smith

  DOI：10.1016/s0022-1139(00)80902-1

  日期：1985.1

  The reactions of various fluoroaromatics, C6F6−xHx, and C6F5X (X = C6F6, Cl, Me, NO2, CF3, COCl, CH2Br, OMe, and NH2) with lead(II) benzenethiolate in DMF have been examined. Lead thiolate acted as an excellent source of benzenethiolate anions and displacement of fluorine, chlorine or the nitro group was observed. The new products have been characterized by elemental analysis, and NMR (H−1 and F−19)

  各种氟代芳烃，C 6 F 6-x H x和C 6 F 5 X（X = C 6 F 6，Cl，Me，NO 2，CF 3，COCl，CH 2 Br，OMe和NH 2的反应）中已检测了DMF中的苯硫醇铅（II）。硫醇铅是苯硫醇根阴离子的极好来源，并观察到了氟，氯或硝基的置换。这些新产品已通过元素分析，NMR（H-1和F-19），红外和质谱进行了表征。
• The thiolate anion as a nucleophile. Part XIII. Reactions of some tin(II) aromatic thiolates
  作者：Rosemary C. Hynes、Michael E. Peach

  DOI：10.1016/s0022-1139(00)80528-x

  日期：1986.3

  The reactions of tin(II) benzenethiolate and p-toluenethiolate with various fluoroaromatics in DMF have been studied. Replacement of some of the aromatic fluorines by the thiolate group was observed. The tin(II) aromatic thiolates are comparable in reactivity in these reactions with lead(II) benzenethiolate. All new compounds have been characterized by elemental analysis, and NMR (H-1 and F-19) and

  研究了苯硫醇锡（II）和对甲苯硫醇锡与DMF中各种氟代芳烃的反应。观察到一些芳族氟被硫醇盐基团取代。在这些反应中，锡（II）芳族硫醇盐与苯硫醇铅（II）具有可比性。所有新化合物均已通过元素分析，NMR（H-1和F-19）和质谱进行了表征。
• Aromatic polyfluoro-compounds. Part LIV. Copper-assisted nucleophilic displacement reactions of pentafluorohalogenobenzenes
  作者：J. Burden、P. L. Coe、C. R. Marsh、J. C. Tatlow

  DOI：10.1039/p19720000763

  日期：——

  Copper-assisted nucleophilic displacement reactions of pentafluorohalogenobenzenes have been investigated; in some cases exclusive halogen replacement occurs, and in others fluorine displacement and halogen reduction are observed. The effects of solvent and added ligands, notably thiourea, on the course of the reaction have been studied and a theory developed to explain the results observed.

  已经研究了铜辅助五氟卤代苯的亲核取代反应。在某些情况下，发生了唯一的卤素替代，而在另一些情况下，观察到氟置换和卤素还原。研究了溶剂和添加的配体（特别是硫脲）对反应过程的影响，并开发了一种理论来解释所观察到的结果。
• Gurin, G. G.; Avramenko, A. A.; Nikonorov, Yu. I., Journal of Organic Chemistry USSR (English Translation), 1981, p. 1340 - 1345
  作者：Gurin, G. G.、Avramenko, A. A.、Nikonorov, Yu. I.、Yakobson, G. G.

  DOI：——

  日期：——
• FURIN G. G.; AVRAMENKO A. A.; NIKONOROV YU. I.; YAKOBSON G. G., ZH. ORGAN. XIMII, 1981, 17, HO 7, 1505-1511
  作者：FURIN G. G.、 AVRAMENKO A. A.、 NIKONOROV YU. I.、 YAKOBSON G. G.

  DOI：——

  日期：——