1-Phenyl-2-methylsulfonyl-aethylacetat | 67728-18-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-Phenyl-2-methylsulfonyl-aethylacetat
• 英文别名: (2-Methylsulfonyl-1-phenylethyl) acetate
• CAS: 67728-18-1
• 化学式: C₁₁H₁₄O₄S
• 分子量: 242.296
• InChiKey: DVCGOZAOSYQTHZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  16
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  68.8
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• Releasable GLP-1 conjugates
  申请人：QuiaPEG Pharmaceuticals AB

  公开号：US11357828B2

  公开（公告）日：2022-06-14

  The present application provides compounds of Formula (I): or pharmaceutically acceptable salts thereof, wherein D is a residue of a GLP-polypeptide or an analog thereof, which underdo hydrolysis under physiological conditions to release the GLP-polypeptide or analog thereof and which are useful in the treatment of disorders that could be beneficially treated with the GLP-polypeptide or analog thereof.

  本申请提供了式 (I) 化合物： 或其药学上可接受的盐，其中 D 是 GLP 多肽或其类似物的残基，在生理条件下可水解释放出 GLP 多肽或其类似物，可用于治疗可使用 GLP 多肽或其类似物进行有益治疗的疾病。
• RELEASABLE GLP-1 CONJUGATES
  申请人：QuiaPEG Pharmaceuticals AB

  公开号：US20220118055A1

  公开（公告）日：2022-04-21

  The present application provides compounds of Formula (I): or pharmaceutically acceptable salts thereof, wherein D is a residue of a GLP-polypeptide or an analog thereof, which underdo hydrolysis under physiological conditions to release the GLP-polypeptide or analog thereof and which are useful in the treatment of disorders that could be beneficially treated with the GLP-polypeptide or analog thereof.