4-(4-Dimethylaminophenyl)-2,6-diphenylthiopyrylium | 47551-78-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 硫吡喃类
• 英文名称: 4-(4-Dimethylaminophenyl)-2,6-diphenylthiopyrylium
• 英文别名: 4-[4-(Dimethylamino)phenyl]-2,6-diphenylthiopyranium；[4-(2,6-diphenylthiopyran-4-ylidene)cyclohexa-2,5-dien-1-ylidene]-dimethylazanium
• CAS: 47551-78-0
• 化学式: C₂₅H₂₂NS
• 分子量: 368.522
• InChiKey: IWBBAVPUHLAWGW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.2
• 重原子数：
  27
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  28.3
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  4-(4-Dimethylaminophenyl)-2,6-diphenylthiopyrylium 在 甲醇 、 sodium methylate 作用下， 以83%的产率得到4-(4-Dimethylamino-phenyl)-2-methoxy-2,6-diphenyl-2H-thiopyran
  参考文献：
  名称：

  Fischer, Gerhard W.; Zimmermann, Thomas, Zeitschrift fur Chemie, 1983, vol. 23, # 9, p. 333 - 334

  摘要：

  DOI：
• 作为产物：
  描述：

  4-(4-Dimethylamino-phenyl)-2-methoxy-2,6-diphenyl-2H-thiopyran 在 氢气 作用下， 生成 4-(4-Dimethylaminophenyl)-2,6-diphenylthiopyrylium
  参考文献：
  名称：

  Fischer, Gerhard W.; Zimmermann, Thomas, Zeitschrift fur Chemie, 1983, vol. 23, # 9, p. 333 - 334

  摘要：

  DOI：

文献信息

• Multi-channel receptors based on thiopyrylium functionalised with macrocyclic receptors for the recognition of transition metal cations and anions
  作者：T. Ábalos、D. Jiménez、M. Moragues、S. Royo、R. Martínez-Máñez、F. Sancenón、J. Soto、A. M. Costero、M. Parra、S. Gil

  DOI：10.1039/b921486k

  日期：——

  We report herein the synthesis and characterization of a family of ligands containing different cation binding sites covalently connected to a thiopyrylium signalling reporter. The receptors L1–L6 are able to signal the presence of certain metal cations via three different channels; i.e. electrochemically, fluorogenically and chromogenically. An acetonitrile solution of L1–L6 shows a bright blue colour

  我们在此报告了一系列共价连接至硫代吡啶鎓信号传导报告子的配体家族的合成和表征，所述配体家族包含不同的阳离子结合位点。受体L 1 – L 6能够通过三个不同的通道发出某些金属阳离子的信号。即电化学地，荧光地和发色地。一个乙腈L 1 – L 6的溶液由于在575–585 nm范围内的电荷转移带而显示出亮蓝色。颜色变化乙腈的大号1 -大号6在金属阳离子的存在银+， 镉2+， 铜2+， 铁3+， 汞2+， 镍2+， 铅2+ 和 锌2+已经研究过了。对于系统L 4 -Pb 2+和L 5 -Hg 2+，发现了蓝带的选择性七色移。另外，L 1 - L 6的荧光较差，但与某些金属阳离子的配位会导致约500 nm处的荧光增强。例如，存在铜2+ 和 铁3+分别导致以500 nm为中心的L 1的发射强度显着提高42倍和45倍。同样显着的是在存在四氢呋喃的情况下，L 4和L 5的观察到的18倍增强。铁3+ 和 铜2+，
• Photoconductive elements which are sensitive to near-infrared radiation
  申请人：EASTMAN KODAK COMPANY

  公开号：EP0491316A1

  公开（公告）日：1992-06-24

  Photoconductive elements which have high sensitivity to radiation in the near-infrared region of the electromagnetic spectrum comprise a conductive support, a charge generation material which comprises a near-infrared-sensitive organic pigment, and, electrically contiguous with the charge generation material, an aggregate photoconductive material.

  对电磁波谱近红外区辐射具有高灵敏度的光电导元件包括导电支架、由近红外敏感有机颜料组成的电荷发生材料以及与电荷发生材料电连接的聚合光电导材料。
• Fluorescent stain containing pyrylium salt or its similar salt, detection method of nucleic acid by use of it, and fluorescent staining method of biological sample
  申请人：CANON KABUSHIKI KAISHA

  公开号：EP0603783A1

  公开（公告）日：1994-06-29

  A stain for a nucleic acid characterized by containing, as an effective component, a pyrylium salt compound having Y as a negative portion and a pyrylium ring or a pyrylium-similar ring, wherein the ring is comprised of X selected from O, S, Se and Te as a hetero atom and has substituents R¹, R² and R³, wherein each of R¹ and R² is independently a hydrogen atom, sulfonate group, amino group, substituted or unsubstituted aryl group, etc., R³ is -A or -L-A, L is -L¹-, -L²-L³- or -L⁴-L⁵-L⁶-, and each of L¹ to L⁶ is independently -(CH=CH)-, a divalent group derived from the substituted or unsubstituted aryl group, etc., A is a substituted or unsubstituted aryl group, etc., and Y⁻ is an anion. A method for detecting a nucleic acid which comprises the steps of reacting a sample with the stain, and then detecting, by an optical means, the double-strand nucleic acid stained with the stain in the case that the double-strand nucleic acid is contained in the sample.

  一种用于核酸的染色剂，其特征在于作为有效成分含有一种吡鎓盐化合物，该化合物以Y为负极部分，具有吡鎓环或吡鎓类似环，其中该环由选自O、S、Se和Te的X作为杂原子组成，并具有取代基R¹、R²和R³，其中R¹和R²各自独立地为氢原子、磺酸基、氨基、取代或未取代的芳基等、R³是-A或-L-A，L是-L¹-、-L²-L³-或-L⁴-L⁵-L⁶-，其中L¹至L⁶各自独立地是-(CH=CH)-、衍生自取代或未取代芳基等的二价基团，A是取代或未取代芳基等，Y-是阴离子。一种检测核酸的方法，包括以下步骤：将样品与染色剂反应，然后在样品中含有双链核酸的情况下，通过光学手段检测被染色剂染色的双链核酸。
• Light curable dental composition
  申请人：NIPPON OIL AND FATS COMPANY, LIMITED

  公开号：EP0176777B1

  公开（公告）日：1989-11-23
• Fluorescent stain containing pyrylium salt or its similar salt, detection method of nucleic acid by use of it
  申请人：CANON KABUSHIKI KAISHA

  公开号：EP0603783B1

  公开（公告）日：2001-09-26