5-bromo-2,4-dimethyl-6-oxo-1-propylamino-1,6-dihydro-pyridine-3-carboxylic acid [(S)-1-(4-chloro-phenyl)-propyl]-amide | 1310922-38-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 5-bromo-2,4-dimethyl-6-oxo-1-propylamino-1,6-dihydro-pyridine-3-carboxylic acid [(S)-1-(4-chloro-phenyl)-propyl]-amide
• 英文别名: 5-bromo-N-[(1S)-1-(4-chlorophenyl)propyl]-2,4-dimethyl-6-oxo-1-(propylamino)pyridine-3-carboxamide
• CAS: 1310922-38-3
• 化学式: C₂₀H₂₅BrClN₃O₂
• 分子量: 454.794
• InChiKey: VJMCZHOSNRMTBH-INIZCTEOSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  27
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  61.4
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• Pyridone derivatives as NK3 antagonists
  申请人：Khanzhin Nikolay

  公开号：US20110144164A1

  公开（公告）日：2011-06-16

  The present invention relates to compounds useful in therapy, in particular in the treatment of psychosis, to compositions comprising said compounds, and to methods of treating diseases comprising the administration of said compounds.

  本发明涉及在治疗中有用的化合物，特别是在治疗精神病方面，涉及包含该化合物的组合物，以及包括给予该化合物的治疗方法。
• [EN] PYRIDONE DERIVATIVES AS NK3 ANTAGONISTS<br/>[FR] DÉRIVÉS DE PYRIDONE ANTAGONISTES DE NK3
  申请人：LUNDBECK & CO AS H

  公开号：WO2011072691A1

  公开（公告）日：2011-06-23

  The present invention relates to compound of formula (I) useful in therapy, in particular in the treatment of psychosis, to compositions comprising said compounds, and to methods of treating diseases comprising the administration of said compounds.

  本发明涉及一种具有式（I）的化合物，用于治疗，特别是在治疗精神病方面，包括所述化合物的组合物，以及通过给予该化合物来治疗疾病的方法。
• Photocurable dry film, method for preparing same, patterning method and film for protecting electric and electronic parts
  申请人：Shin-Etsu Chemical Co., Ltd.

  公开号：EP2364847A1

  公开（公告）日：2011-09-14

  Disclosed herein is a photocurable dry film including a structure having a photocurable resin layer sandwiched between a support film and a protective film, the photocurable resin layer being formed of a photocurable resin composition including ingredients (A) to (D): (A) a silicone skeleton-containing polymer compound having the repeating units represented by the following general formula (1) wherein X and Y, respectively, a divalent organic group represented by the following general formula (2) or (3) wherein wherein (B) a crosslinking agent selected from formalin-modified or formalin-alcohol-modified amino condensates and phenolic compound having on average two or more methylol groups or alkoxymethylol groups in one molecule; (C) a photoacid generator capable of generating an acid by decomposition with light having a wavelength of 190 to 500 nm; and (D) a solvent.

  本文公开了一种光固化干膜，其结构包括夹在支撑膜和保护膜之间的光固化树脂层，光固化树脂层由包括成分(A)至(D)的光固化树脂组合物形成： (A) 含有机硅骨架的聚合物化合物，其重复单元由以下通式（1）表示 其中 X 和 Y 分别是由以下通式（2）或（3）表示的二价有机基团 其中 其中 (B) 选自福尔马林改性或福尔马林-酒精改性的氨基缩合物和酚类化合物的交联剂，它们在一个分子中平均具有两个或两个以上的甲醇基团或烷氧基甲醇基团； (C) 光酸发生器，能够通过波长为 190 至 500 纳米的光分解生成酸；以及 (D) 溶剂。
• PHOTOCURABLE DRY FILM, METHOD FOR PREPARING SAME, PATTERNING METHOD AND FILM FOR PROTECTING ELECTRIC AND ELECTRONIC PARTS
  申请人：Shin-Etsu Chemical Co., Ltd.

  公开号：EP2364847B1

  公开（公告）日：2015-07-22
• US8729148B2
  申请人：——

  公开号：US8729148B2

  公开（公告）日：2014-05-20