4-bromo-2,3-dimethyl-6-nitrophenylazide | 547755-90-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-bromo-2,3-dimethyl-6-nitrophenylazide
• 英文别名: 4-Azido-1-bromo-2,3-dimethyl-5-nitrobenzene
• CAS: 547755-90-8
• 化学式: C₈H₇BrN₄O₂
• 分子量: 271.073
• InChiKey: ALDRYRBSXGICOL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  15
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  60.2
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  4-bromo-2,3-dimethyl-6-nitrophenylazide 在 三苯基膦 作用下， 以 xylene 、 二乙二醇 为溶剂， 反应 9.0h， 生成 6-bromo-4,5-dimethylbenzofurazan
  参考文献：
  名称：

  Synthesis of Quinoxaline 1,4-Dioxides from Benzofuroxan Proceeds Not in, But on Zeolite

  摘要：

  Quinoxaline synthesis using Na-zeolite A as a catalyst to proceeds in a better yield than that using zeolite X. The pore diameter of zeolite X is large enough to allow the benzofuroxan derivatives access to cages, therefore part of benzofuroxan is adsorbed in the internal surface of zeolite X. Whereas the windows to the cages of Na-zeolite A are too small to allow the benzofuroxan derivatives access to the cages, therefore all the benzofuroxan is adsorbed on the external surface of zeolite. The reactions of benzofuroxans with benzoylacetone was catalyzed by zeolite proceed not in, but on zeolite.

  DOI：

  10.3987/com-02-9661
• 作为产物：
  描述：

  4-溴-2,3-二甲基-6-硝基苯胺 在 硫酸 、 水 、 sodium nitrite 、 sodium azide 作用下， 反应 0.5h， 以98%的产率得到4-bromo-2,3-dimethyl-6-nitrophenylazide
  参考文献：
  名称：

  Synthesis of Quinoxaline 1,4-Dioxides from Benzofuroxan Proceeds Not in, But on Zeolite

  摘要：

  Quinoxaline synthesis using Na-zeolite A as a catalyst to proceeds in a better yield than that using zeolite X. The pore diameter of zeolite X is large enough to allow the benzofuroxan derivatives access to cages, therefore part of benzofuroxan is adsorbed in the internal surface of zeolite X. Whereas the windows to the cages of Na-zeolite A are too small to allow the benzofuroxan derivatives access to the cages, therefore all the benzofuroxan is adsorbed on the external surface of zeolite. The reactions of benzofuroxans with benzoylacetone was catalyzed by zeolite proceed not in, but on zeolite.

  DOI：

  10.3987/com-02-9661