2-Bromo-4-methyl-6-phenylphenol | 620987-86-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-Bromo-4-methyl-6-phenylphenol
• CAS: 620987-86-2
• 化学式: C₁₃H₁₁BrO
• 分子量: 263.134
• InChiKey: QBTKQDITDPXZGQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  15
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• [EN] BENZOTHIAZOLE MACROCYCLES AS INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION<br/>[FR] UTILISATION DE MACROCYCLES DE BENZOTHIAZOLE COMME QU'INHIBITEURS DE LA RÉPLICATION DU VIRUS DE L'IMMUNODÉFICIENCE HUMAINE
  申请人：BRISTOL MYERS SQUIBB CO

  公开号：WO2015123230A1

  公开（公告）日：2015-08-20

  The disclosure generally relates to compounds of formula (I), including compositions and methods for treating human immunodeficiency virus (HIV) infection. The disclosure provides novel inhibitors of HIV, pharmaceutical compositions containing such compounds, and methods for using these compounds in the treatment of HIV infection.

  本公开涉及式(I)的化合物，包括用于治疗人类免疫缺陷病毒（HIV）感染的组合物和方法。本公开提供了HIV的新型抑制剂，含有这些化合物的药物组合物，以及在治疗HIV感染中使用这些化合物的方法。
• PHENOL-HETEROCYCLIC LIGANDS, METAL COMPLEXES, AND THEIR USES AS CATALYSTS
  申请人：Leclerc Margarete K.

  公开号：US20100048841A1

  公开（公告）日：2010-02-25

  Ligands, compositions, and metal-ligand complexes that incorporate phenol-heterocyclic compounds are disclosed that are useful in the catalysis of transformations such as the polymerization of monomers into polymers. The catalysts have high performance characteristics, including high comonomer incorporation into ethylene/olefin copolymers, where such olefins are for example, 1-octene, propylene or styrene. The catalysts particularly polymerize styrene to form polystyrene.

  本发明揭示了包含酚-杂环化合物的配体、组合物和金属配合物，这些配体、组合物和金属配合物在催化转化中非常有用，例如将单体聚合成聚合物。催化剂具有高性能特征，包括将共聚单体高度并入乙烯/烯烃共聚物中，其中所述烯烃例如为1-辛烯、丙烯或苯乙烯。该催化剂特别是将苯乙烯聚合成聚苯乙烯。
• TRANSITION METAL COMPLEX, PROCESS FOR THE PREPARATION THEREOF, POLYMERIZATION CATALYST FOR OLEFINS CONTAINING THE COMPLEX, AND PROCESS FOR PRODUCING OLEFIN POLYMERS
  申请人：Sumitomo Chemical Company, Limited

  公开号：EP0842939A1

  公开（公告）日：1998-05-20

  A transition metal complex represented by the formula (1) wherein M1 is a transition metal atom of the group 4 of the periodic table of elements, A is an atom of the group 16 of the periodic table of elements, and B is an atom of the group 14 of the periodic table of elements; Cp1 is a group having a cyclopentadiene type anionic skeleton; and X1, X2, R1, R2, R3, R4, R5 and R6 are each independently a hydrogen atom, halogen atom, alkyl group with the number of carbon atoms of 1-20 optionally substituted with at least one halogen atom, aralkyl group with the number of carbon atoms of 7-20 optionally substituted with at least one halogen atom, aryl group with the number of carbon atoms of 6-20 optionally substituted with at least one halogen atom, substituted silyl group with the number of carbon atoms of 1-20 optionally substituted with at least one halogen atom, alkoxy group with the number of carbon atoms of 1-20 optionally substituted with at least one halogen atom, aralkyloxy group with the number of carbon atoms of 7-20 optionally substituted with at least one halogen atom or aryloxy group with the number of carbon atoms of 6-20 optionally substituted with at least one halogen atom, or di-substituted amino group with the number of carbon atoms of 2-20, provided that R1, R2, R3, R4, R5 and R6 may optionally combine with each other to form a ring; a process for producing the same; an olefin polymerization catalyst containing the transition metal complex; and a process for producing olefin polymers.

  一种由式（1）表示的过渡金属配合物 其中 M1 是元素周期表中第 4 族的过渡金属原子，A 是元素周期表中第 16 族的原子，B 是元素周期表中第 14 族的原子；Cp1 是具有环戊二烯型阴离子骨架的基团；X1、X2、R1、R2、R3、R4、R5 和 R6 各自独立地为氢原子、卤素原子、碳原子数为 1-20 的烷基（可选地被至少一个卤素原子取代）、碳原子数为 7-20 的芳烷基（可选地被至少一个卤素原子取代）、碳原子数为 6-20 的芳烷基（可选地被至少一个卤素原子取代）、碳原子数为 1-20 的取代硅烷基（可选地被至少一个卤素原子取代）、碳原子数为 1-20 个、可任选被至少一个卤素原子取代的烷氧基，碳原子数为 7-20 个、可任选被至少一个卤素原子取代的烷氧基，或碳原子数为 6-20 个、可任选被至少一个卤素原子取代的芳氧基，或碳原子数为 2-20 个的二取代氨基，条件是 R1、R2、R3、R4、R5 和 R6 可任选相互结合形成一个环；生产上述物质的工艺；含有过渡金属复合物的烯烃聚合催化剂；以及生产烯烃聚合物的工艺。
• Transition metal complex, process for producing the same, olefin polymerization catalyst containing the transition metal complex and process for producing olefin polymers
  申请人：Sumitomo Chemical Company, Limited

  公开号：EP1498178A2

  公开（公告）日：2005-01-19

  A transition metal complex represented by the formula (1) wherein M1 is a transition metal atom of the group 4 of the periodic table of elements; A is an atom of the group 16 of the periodic table of elements, and B is an atom of the group 14 of the periodic table of elements; Cp1 is a group having a cyclopentadiene type anionic skeleton; and X1, X2, R1, R2, R3, R4, R5 and R6 are each independently a hydrogen atom, halogen atom, alkyl group with the number of carbon atoms of 1-20 optionally substituted with at least one halogen atom, aralkyl group with the number of carbon atoms of 7-20 optionally substituted with at least one halogen atom, aryl group with the number of carbon atoms of 6-20 optionally substituted with at least one halogen atom, substituted silyl group with the number of carbon atoms of 1-20 optionally substituted with at least one halogen atom, alkoxy group with the number of carbon atoms of 1-20 optionally substituted with at least one halogen atom, aralkyloxy group with the number of carbon atoms of 7-20 optionally substituted with at least one halogen atom or aryloxy group with the number of carbon atoms of 6-20 optionally substituted with at least one halogen atom, or di-substituted amino group with the number of carbon atoms of 2-20, provided that R1, R2, R3, R4, R5 and R6 may optionally combine with each other to form a ring; a process for producing the same; an olefin polymerization catalyst containing the transition metal complex; and a process for producing olefin polymers.

  一种由式（1）表示的过渡金属配合物 其中 M1 是元素周期表中第 4 族的过渡金属原子；A 是元素周期表中第 16 族的原子，B 是元素周期表中第 14 族的原子；Cp1 是具有环戊二烯型阴离子骨架的基团；X1、X2、R1、R2、R3、R4、R5 和 R6 各自独立地为氢原子、卤素原子、碳原子数为 1-20 的烷基（可选地被至少一个卤素原子取代）、碳原子数为 7-20 的芳烷基（可选地被至少一个卤素原子取代）、碳原子数为 6-20 的芳烷基（可选地被至少一个卤素原子取代）、碳原子数为 1-20 的取代硅烷基（可选地被至少一个卤素原子取代）、碳原子数为 1-20 个、可任选被至少一个卤素原子取代的烷氧基，碳原子数为 7-20 个、可任选被至少一个卤素原子取代的烷氧基，或碳原子数为 6-20 个、可任选被至少一个卤素原子取代的芳氧基，或碳原子数为 2-20 个的二取代氨基，条件是 R1、R2、R3、R4、R5 和 R6 可任选相互结合形成一个环；生产上述物质的工艺；含有过渡金属复合物的烯烃聚合催化剂；以及生产烯烃聚合物的工艺。
• OLEFIN POLYMERIZATION CATALYST CONTAINING A TRANSITION METAL COMPLEX AND PROCESS FOR PRODUCING OLEFIN POLYMERS
  申请人：Sumitomo Chemical Company, Limited

  公开号：EP0842939B1

  公开（公告）日：2004-10-06