N,N'-Di-p-sulfamoylphenylbiphenyl-4,4'-disulfonamid | 53999-53-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N,N'-Di-p-sulfamoylphenylbiphenyl-4,4'-disulfonamid
• 英文别名: Sulfonamide, 11；N-(4-sulfamoylphenyl)-4-[4-[(4-sulfamoylphenyl)sulfamoyl]phenyl]benzenesulfonamide
• CAS: 53999-53-4
• 化学式: C₂₄H₂₂N₄O₈S₄
• 分子量: 622.725
• InChiKey: UMBLVQMFLFFKSP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  40
• 可旋转键数：
  9
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  246
• 氢给体数：
  4
• 氢受体数：
  12

反应信息

• 作为产物：
  描述：

  4,4'-biphenyldisulfonyl chloride 、 磺胺 在 吡啶 作用下， 以 乙醚 为溶剂， 反应 4.0h， 生成 N,N'-Di-p-sulfamoylphenylbiphenyl-4,4'-disulfonamid
  参考文献：
  名称：

  Investigation of Cationic Surfactants and Sulfonamides and Their Nanoparticles as Biocides Against Sulfur Reducing Bacteria in the Petroleum Industry

  摘要：

  A series of cationic ammonium surfactants (1-3) and sulfonamides (4-5) were synthesized and characterized using elemental analysis and FT-IR spectroscopy. The nanostructures of the synthesized surfactants and sulfonamides as silver and zinc nanoparticles (Ag/ZnNPs) were prepared and characterized using transmission electron microscope. The TEM image of AgN-1-3 is a spherical shape with narrow diameter, whereas ZnN-4-6 composites are roughly spherical. The size analysis demonstrated the average diameter of 50-55nm for the composite. The antimicrobial activity of the synthesized surfactants and sulfonamides as well as their nanostructures were investigated as potential biocides against sulfur reducing bacteria. The values of the inhibition zone diameters are gradually increased by increasing the concentration of the tested biocides and the maximum inhibition diameters for all biocides are obtained at 5mg/mL. The results also showed that the sulfonamides and their nanocomposites have higher biocidal activities than those of the cationic ammonium surfactants biocides and their nanoparticles.

  DOI：

  10.1080/15533174.2013.778877

文献信息

• Investigation of Cationic Surfactants and Sulfonamides and Their Nanoparticles as Biocides Against Sulfur Reducing Bacteria in the Petroleum Industry
  作者：Salwa M. I. Morsy、Mohamed M. Ibrahim

  DOI：10.1080/15533174.2013.778877

  日期：2014.4.21

  A series of cationic ammonium surfactants (1-3) and sulfonamides (4-5) were synthesized and characterized using elemental analysis and FT-IR spectroscopy. The nanostructures of the synthesized surfactants and sulfonamides as silver and zinc nanoparticles (Ag/ZnNPs) were prepared and characterized using transmission electron microscope. The TEM image of AgN-1-3 is a spherical shape with narrow diameter, whereas ZnN-4-6 composites are roughly spherical. The size analysis demonstrated the average diameter of 50-55nm for the composite. The antimicrobial activity of the synthesized surfactants and sulfonamides as well as their nanostructures were investigated as potential biocides against sulfur reducing bacteria. The values of the inhibition zone diameters are gradually increased by increasing the concentration of the tested biocides and the maximum inhibition diameters for all biocides are obtained at 5mg/mL. The results also showed that the sulfonamides and their nanocomposites have higher biocidal activities than those of the cationic ammonium surfactants biocides and their nanoparticles.