4-乙酰基环己基氯苯 | 91161-85-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 4-乙酰基环己基氯苯
• 中文别名: 反式-4-(4-氯苯基)-1-乙酰基环己烷
• 英文名称: trans-4-(p-Chlorophenyl)-1-acetylcyclohexane
• 英文别名: 1-[4-(4-chlorophenyl)cyclohexyl]ethanone
• CAS: 91161-85-2；95233-36-6
• 化学式: C₁₄H₁₇ClO
• 分子量: 236.73
• InChiKey: FLHSIPCMAJDSGB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

安全信息

• 海关编码：
  2914700090

文献信息

• [EN] SUBSTITUTED AMINOTHIAZOLE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE<br/>[FR] DÉRIVÉS D'AMINOTHIAZOLE SUBSTITUÉS, COMPOSITIONS PHARMACEUTIQUES ET LEURS PROCÉDÉS D'UTILISATION
  申请人：TRANSTECH PHARMA INC

  公开号：WO2010025142A1

  公开（公告）日：2010-03-04

  Substituted aminothiazole derivatives, methods of their preparation, pharmaceutical compositions comprising a substituted aminothiazole, and methods of use in treating human or animal disorders. The compounds may be useful as inhibitors of action of AgRP on a melanocortin receptor and thus may be useful for the management, treatment, control, or the adjunct treatment of diseases which may be responsive to the modulation of melanocortin receptors including obesity-related disorders.

  替代氨基噻唑衍生物，其制备方法，含有替代氨基噻唑的药物组合物，以及在治疗人类或动物疾病中的使用方法。这些化合物可能作为AgRP对黑色素皮质素受体作用的抑制剂而有用，因此可能有助于管理、治疗、控制或辅助治疗对黑色素皮质素受体调节敏感的疾病，包括与肥胖相关的疾病。
• PROCESS FOR THE PREPARATION OF ATOVAQUONE
  申请人：Dwyer Andrew Neil

  公开号：US20130267717A1

  公开（公告）日：2013-10-10

  Disclosed herein is novel process for preparation of atovaquone, which process includes reacting 1H-2-benzopyran-1,4(3H)-dione with 4-(4-chlorophenyl)cyclohexanecarbaldehyde. The invention further discloses novel intermediates useful in the preparation of atovaquone.

  本文披露了一种新的阿托伐醌制备过程，该过程包括将1H-2-苯并吡喃-1,4（3H）-二酮与4-(4-氯苯基)环己烷-1-甲醛反应。本发明还披露了在制备阿托伐醌中有用的新中间体。
• Substituted Aminothiazole Derivatives, Pharmaceutical Compositions, And Methods Of Use
  申请人：Mjalli Adnan M. M.

  公开号：US20100056587A1

  公开（公告）日：2010-03-04

  Substituted aminothiazole derivatives, methods of their preparation, pharmaceutical compositions comprising a substituted aminothiazole, and methods of use in treating human or animal disorders. The compounds may be useful as inhibitors of action of AgRP on a melanocortin receptor and thus may be useful for the management, treatment, control, or the adjunct treatment of diseases which may be responsive to the modulation of melanocortin receptors including obesity-related disorders.

  替代氨噻唑衍生物，其制备方法，含有替代氨噻唑的药物组合物，以及在治疗人类或动物疾病中使用的方法。这些化合物可能有用作为AgRP对黑色素皮质素受体的作用抑制剂，因此可能有用于管理、治疗、控制或辅助治疗可能对黑色素皮质素受体调节敏感的疾病，包括与肥胖相关的疾病。
• NOVEL ANTIBACTERIAL AGENTS FOR THE TREATMENT OF GRAM POSITIVE INFECTIONS
  申请人：Metcalf, III Chester A.

  公开号：US20140073558A1

  公开（公告）日：2014-03-13

  The present invention relates to novel lipopeptide compounds, pharmaceutical compositions of these compounds and methods of using these compounds as antibacterial compounds. The compounds of the invention are particularly useful against a variety of bacteria, including resistant strains. The compounds are useful as antibacterial agents against Clostridium difficile.

  本发明涉及一种新型的脂肽化合物，以及这些化合物的药物组合物和将这些化合物用作抗菌化合物的方法。本发明中的化合物特别适用于对抗各种细菌，包括抗药性菌株。这些化合物可用作抗Clostridium difficile的抗菌剂。
• 1-(Trans-4-alkylcyclohexyl)-2-(trans-4'-(p-substituted phenyl)cyclohexyl)ethane and liquid crystal mixture
  申请人：ASAHI GLASS COMPANY LTD.

  公开号：EP0102047A1

  公开（公告）日：1984-03-07

  A compound represented by the general formula: where X is a halogen atom, an alkyl group having from 1 to 8 carbon atoms or a cyano group, and R is an alkyl group having from 1 to 8 carbon atoms.

  通式如下的化合物 其中 X 是卤素原子、1 至 8 个碳原子的烷基或氰基，R 是 1 至 8 个碳原子的烷基。