3-amino-1-methyl-pyridinium | 45642-86-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 3-amino-1-methyl-pyridinium
• 英文别名: 3-Amino-1-methylpyridinium；1-methylpyridin-1-ium-3-amine
• CAS: 45642-86-2
• 化学式: C₆H₉N₂
• 分子量: 109.151
• InChiKey: MVZHRMOZEJOWBB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.3
• 重原子数：
  8
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  29.9
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• Enzyme inhibitors
  申请人：Gil Martinez Ana

  公开号：US20080033012A1

  公开（公告）日：2008-02-07

  Compounds of general formula (I): where A, E, G, X, Y and the bond - - - take various meanings are of use in the preparation of a pharmaceutical formulation, for example in the treatment of a disease in which GSK-3 is involved, including Alzheimer's disease or the non-dependent insulin diabetes mellitus, or hyperproliferative disease such as cancer, displasias or metaplasias of tissue, psoriasis, arteriosclerosis or restenosis.

  通式为（I）的化合物：其中A，E，G，X，Y和键- - -取不同的含义，可用于制备药物配方，例如用于治疗与GSK-3有关的疾病，包括阿尔茨海默病或非依赖胰岛素糖尿病，或增生性疾病，如癌症，组织发育不良或上皮化生，银屑病，动脉硬化或再狭窄。
• Mediators of reverse cholesterol transport for the treatment of hypercholesterolemia
  申请人：Sircar C. Jagadish

  公开号：US20070004644A1

  公开（公告）日：2007-01-04

  The present invention provides compositions adapted to enhance reverse cholesterol transport in mammals. The compositions are suitable for oral delivery and useful in the treatment and/or prevention of hypercholesterolemia, atherosclerosis and associated cardiovascular diseases.

  本发明提供了适用于增强哺乳动物的逆向胆固醇转运的组合物。这些组合物适合口服给药，并且在治疗和/或预防高胆固醇血症、动脉粥样硬化及相关心血管疾病方面非常有用。
• Novel cephalosporin compounds and antibacterial agents
  申请人：MEIJI SEIKA KAISHA LTD.

  公开号：EP0289002A2

  公开（公告）日：1988-11-02

  Novel cephalosporin compounds of the formula (I): wherein R¹ and R² may be the same or different and are a hydrogen atom or a lower alkyl group of 1 - 5 carbon atoms and A is a hydrogen atom or a nucleophilic compound residue or pharmacologically acceptable salts thereof have excellent antibacterial activity against Gram positive and Gram negative microorganisms.

  式(I)的新型头孢菌素化合物： 其中 R¹ 和 R² 可以相同或不同，并且是氢原子或 1 - 5 个碳原子的低级烷基，A 是氢原子或亲核化合物残基或其药理学上可接受的盐，对革兰氏阳性和革兰氏阴性微生物具有极佳的抗菌活性。
• THIADIAZOLIDINONE DERIVATIVES
  申请人：Jordan Craig

  公开号：US20100063109A1

  公开（公告）日：2010-03-11

  The present invention relates to compounds of the formulae herein, their acceptable salts, solvates, hydrates and polymorphs thereof. The compounds of this invention are useful in treatment of disease, particularly leukemia. The invention also provides compositions comprising a compound of this invention and the use of such compositions in methods of treating disease, disorders, or symptoms thereof in a subject.
• Thiadiazolidinone Derivatives
  申请人：Jordan Craig

  公开号：US20160058741A1

  公开（公告）日：2016-03-03

  The present invention relates to compounds of the formulae herein, their acceptable salts, solvates, hydrates and polymorphs thereof. The compounds of this invention are useful in treatment of disease, particularly leukemia. The invention also provides compositions comprising a compound of this invention and the use of such compositions in methods of treating disease, disorders, or symptoms thereof in a subject.