o-phenylenecarbonyl hydrogen phosphite | 6083-14-3

• 分子结构分类: 有机化合物 - 苯类化合物
• 英文名称: o-phenylenecarbonyl hydrogen phosphite
• 英文别名: 2-Hydroxy-4-oxo-4H-benzo<1.3.2>dioxaphosphorin；2-Hydroxy-1,3,2-benzodioxaphosphinin-4-one
• CAS: 6083-14-3
• 化学式: C₇H₅O₄P
• 分子量: 184.088
• InChiKey: HRAUCCGIDQGXEY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  12
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  55.8
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  1-氯-4-(乙烯基氧基)苯 、 o-phenylenecarbonyl hydrogen phosphite 以57%的产率得到o-phenylenecarbonyl <1-(p-chlorophenoxy)ethyl>phosphonate
  参考文献：
  名称：

  Ovchinnikov, V. V.; Cherezov, S. V.; Cherkasov, R. A., Journal of general chemistry of the USSR, 1984, vol. 54, p. 910 - 919

  摘要：

  DOI：

文献信息

• Ovchinnikov, V. V.; Safina, Yu. G.; Cherkasov, R. A., Journal of general chemistry of the USSR, 1988, vol. 58, # 9, p. 1841 - 1852
  作者：Ovchinnikov, V. V.、Safina, Yu. G.、Cherkasov, R. A.、Karataeva, F. Kh.、Pudovik, A. N.

  DOI：——

  日期：——
• OVCHINNIKOV, V. V.;CHEREZOV, S. V.;CHERKASOV, R. A.;PUDOVIK, A. N., ZH. OBSHCH. XIMII, 1984, 54, N 5, 1021-1030
  作者：OVCHINNIKOV, V. V.、CHEREZOV, S. V.、CHERKASOV, R. A.、PUDOVIK, A. N.

  DOI：——

  日期：——
• SYNTHETIC METHODS AND DERIVATIVES OF TRIPHOSPHATE OLIGONUCLEOTIDES
  申请人：Manoharan Muthiah

  公开号：US20120107272A1

  公开（公告）日：2012-05-03

  The invention features a oligonucleotide of formula I, or pharmaceutically acceptable salts, or prodrugs thereof: which are capable of inducing an anti-viral or an antibacterial response, in particular, the induction of type I IFN, IL-18 and/or IL-1β by binding to RIG-I. The invention relates to methods of making and using modified oligonucleotide comprising at least one triphosphate or analogs thereof. The invention further relates to methods for treating various disorders and diseases such as viral infections, bacterial infections, parasitic infections, tumors, allergies, autoimmune diseases, immunodeficiencies and immunosuppression.
• Ovchinnikov, V. V.; Cherezov, S. V.; Cherkasov, R. A., Journal of general chemistry of the USSR, 1984, vol. 54, p. 910 - 919
  作者：Ovchinnikov, V. V.、Cherezov, S. V.、Cherkasov, R. A.、Pudovik, A. N.

  DOI：——

  日期：——