Cyclohexanol, 4-[[(2-amino-3,5-dibromophenyl)methyl]amino]-, acetate (ester), trans- | 100693-16-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Cyclohexanol, 4-[[(2-amino-3,5-dibromophenyl)methyl]amino]-, acetate (ester), trans-
• 英文别名: [4-[(2-amino-3,5-dibromophenyl)methylamino]cyclohexyl] acetate
• CAS: 100693-16-1
• 化学式: C₁₅H₂₀Br₂N₂O₂
• 分子量: 420.14
• InChiKey: DZKHPWCTAQSMJO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  21
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  64.4
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• COMBINATION OF A COMPOUND HAVING THE ABILITY TO REARRANGE A LYSOSOMAL ENZYME AND AMBROXOL AND/OR A DERIVATIVE OF AMBROXOL
  申请人：Centogene IP GmbH

  公开号：EP2793872B1

  公开（公告）日：2021-03-10
• Combination of a Compound Having the Ability to Rearrange a Lysosomal Enzyme and Ambroxol and/or a Derivative of Ambroxol
  申请人：Centogene IP GmbH

  公开号：US20210228560A1

  公开（公告）日：2021-07-29

  The present invention is related to a combination comprising a first constituent and a second constituent, wherein the first constituent is a compound having the ability to rearrange a lysosomal protein, wherein the lysosomal protein has a reduced activity, and wherein the second constituent is Ambroxol and/or a derivative of Ambroxol.
• [EN] COMBINATION OF A COMPOUND HAVING THE ABILITY TO REARRANGE A LYSOSOMAL ENZYME AND AMBROXOL AND/OR A DERIVATIVE OF AMBROXOL<br/>[FR] COMBINAISON D'UN COMPOSÉ AYANT L'APTITUDE À RÉARRANGER UNE ENZYME LYSOSOMALE ET D'AMBROXOL ET/OU D'UN DÉRIVÉ D'AMBROXOL
  申请人：CENTOGENE GMBH

  公开号：WO2013091897A1

  公开（公告）日：2013-06-27

  It is herewith declared that the information stored on the carrier which is submitted together with the international patent application is identical to the written sequence listing of the international patent application.