3-氯-2-甲基苯基氯化镁 | 92667-55-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 3-氯-2-甲基苯基氯化镁
• 英文名称: 3-chloro-2-methylphenylmagnesium chloride
• 英文别名: 3-chloro-2-methyl-phenylmagnesium chloride
• CAS: 92667-55-5
• 化学式: C₇H₆Cl₂Mg
• 分子量: 185.336
• InChiKey: GMLJIWNJCRVELV-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  2.13
• 重原子数：
  10.0
• 可旋转键数：
  1.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  0.0
• 氢给体数：
  0.0
• 氢受体数：
  0.0

反应信息

• 作为反应物：
  描述：

  3-氯-2-甲基苯基氯化镁 在 sodium hydroxide 、 sodium acetate 、 dinitrogen tetraoxide 、 肼 作用下， 以 四氯化碳 、 乙醇 为溶剂， 反应 24.25h， 生成 bis(3-chloro-2-methylphenyl) ketone hydrazone
  参考文献：
  名称：

  Lai, Yee-Hing, Australian Journal of Chemistry, 1991, vol. 44, # 8, p. 1151 - 1155

  摘要：

  DOI：

文献信息

• Synthesis of symmetrical diaryl 1,2-diketones from grignard reagents and 1,1′-Oxalylimidazole
  作者：Reginald H. Mitchell、Vivekanantan S. Iyer

  DOI：10.1016/s0040-4039(00)79200-8

  日期：1993.6

  Symmetrical diaryl 1,2-diketones (α-diketones) are obtained in reasonably good yields when readily accessible 1,1′-oxalylimidazole is treated with two equivalents of an aryl Grignard reagent.

  当使用两当量的芳基格氏试剂处理容易获得的1,1'-氧杂咪唑时，可以以相当好的收率获得对称的二芳基1,2-二酮（α-二酮）。
• Non-ligated Nickel Chloride-Catalyzed Cross-Coupling of Aromatic Grignard Reagents with Aryl Halides
  作者：Yoshiharu Ikoma、Fumio Taya、Ei-ichi Ozaki、Shigeki Higuchi、Yoshitake Naoi、Kiyomi Fuji-i

  DOI：10.1055/s-1990-26816

  日期：——

  The reaction between aryl Grignard reagents and aryl halides in the presence of non-ligated nickel(II) chloride affords the cross-coupling products in high yields (60-98%).

  在无配体的氯化镍(II)存在下，芳基格氏试剂与芳基卤化物之间的反应能以高收率(60-98%)得到交叉偶联产物。
• Phenanthro[1,10-cd:8,9-c′d′]bis[1,2]-dithiole and -diselenole as novel electron donors
  作者：Kazuo Takimiya、Akiko Ohnishi、Yoshio Aso、Tetsuo Otsubo、Fumio Ogura

  DOI：10.1039/c39920000278

  日期：——

  The preparation of the title compounds is reported along with their formation of electrically highly conductive charge-transfer complexes with the common electron acceptors TCNQ, TCNQF4, and DDQ.

  报告了标题化合物的制备过程，以及它们与常见电子受体 TCNQ、TCNQF4 和 DDQ 形成的高导电性电荷转移配合物。
• Process to insecticide intermediate
  申请人：FMC Corporation

  公开号：US04465879A1

  公开（公告）日：1984-08-14

  A 3-halo-2-methylphenylmagnesium halide is cross-coupled with a halobenzene under heterogeneous conditions using palladium metal as catalyst, producing a 3-halo-2-methyl[1,1'-biphenyl].

  使用钯金属作为催化剂，在异相条件下，将3-卤代-2-甲基苯基镁卤化物与卤代苯交叉偶联，生成3-卤代-2-甲基[1,1'-联苯]。
• 3-Isoxazolylphenyl compounds, their preparation and their use
  申请人：BASF Aktiengesellschaft

  公开号：US05256666A1

  公开（公告）日：1993-10-26

  3-Isoxazolylphenyl compounds Ia and Ib ##STR1## where R is halogen; alkyl; haloalkyl; alkoxy; haloalkoxy; alkenyl; haloalkenyl; unsubstituted or substituted phenylethenyl; alkynyl; cycloalkyl; aryl; hetaryl; CO.sub.2 R.sup.6 or CONR.sup.7 R.sup.8, R.sup.6 is hydrogen, alkyl, cycloalkyl or benzyl; R.sup.7 and R.sup.8 are each hydrogen, alkyl, cycloalkyl or benzyl or, together with the nitrogen atom to which they are bonded, form a heterocyclic radical; n is 0, 1 or 2; R.sup.1 is halogen or alkyl; R.sup.2 is hydrogen; alkyl; alkenyl; alkynyl or cyano; R.sup.3 and R.sup.4 independently of one another are each unsubstituted or substituted alkyl, alkenyl, cycloalkyl, phenyl, naphthyl, pyridyl or pyrimidinyl; or R.sup.3 and R.sup.4 together form unsubstituted or substituted alkylene; R.sup.5 is hydrogen; unsubstituted or substituted alkyl or one of the groups stated for R.sup.3 ; X is CH.sub.2, O, S or NR.sup.9 and R.sup.9 is hydrogen, alkyl, cycloalkyl, alkenyl, alkynyl or unsubstituted or substituted benzyl, processes for their preparation, agents containing them and the use thereof.

  Ia和Ib的3-异噁唑基苯基化合物，其中R是卤素；烷基；卤代烷基；烷氧基；卤代烷氧基；烯基；卤代烯基；未取代或取代的苯乙烯基；炔基；环烷基；芳基；杂芳基；CO2R6或CONR7R8，其中R6是氢、烷基、环烷基或苄基；R7和R8分别是氢、烷基、环烷基或苄基，或与它们结合的氮原子一起形成杂环基；n为0、1或2；R1是卤素或烷基；R2是氢、烷基、烯基、炔基或氰基；R3和R4各自独立地是未取代或取代的烷基、烯基、环烷基、苯基、萘基、吡啶基或嘧啶基；或R3和R4一起形成未取代或取代的烷基；R5是氢、未取代或取代的烷基或上述R3基团之一；X是CH2、O、S或NR9，R9是氢、烷基、环烷基、烯基、炔基或未取代或取代的苄基。其制备方法、含有它们的制剂以及它们的用途。