3-((3-Dimethylamino-propyl)-{3-[(9H-fluoren-9-ylmethoxycarbonyl)-isobutyl-amino]-propionyl}-amino)-propionic acid | 901123-85-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 芴
• 英文名称: 3-((3-Dimethylamino-propyl)-{3-[(9H-fluoren-9-ylmethoxycarbonyl)-isobutyl-amino]-propionyl}-amino)-propionic acid
• CAS: 901123-85-1
• 化学式: C₃₀H₄₁N₃O₅
• 分子量: 523.673
• InChiKey: IIMWAVQUJKVIOW-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  3-((3-Dimethylamino-propyl)-{3-[(9H-fluoren-9-ylmethoxycarbonyl)-isobutyl-amino]-propionyl}-amino)-propionic acid 、 乙酸酐 、 alkaline earth salt of/the/ methylsulfuric acid 生成
  参考文献：
  名称：

  Antimicrobial β-peptoids by a block synthesis approach

  摘要：

  Antimicrobial peptides and their mimetics offer a potential new disinfective tool. beta-Peptoids (oligo-N-substituted beta-alanines) were synthesized and investigated for antimicrobial activity. A block approach whereby di- and tri-beta-peptoids were first prepared and then ligated via amide bond formation to synthesize larger beta-peptoids was developed. The beta-peptoids were found to possess moderate activity in an Escheridchia coli assay. (C) 2005 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2005.11.075
• 作为产物：
  描述：

  3-((3-Dimethylamino-propyl)-{3-[(9H-fluoren-9-ylmethoxycarbonyl)-isobutyl-amino]-propionyl}-amino)-propionic acid tert-butyl ester 在 甲酸 作用下， 反应 12.0h， 生成 3-((3-Dimethylamino-propyl)-{3-[(9H-fluoren-9-ylmethoxycarbonyl)-isobutyl-amino]-propionyl}-amino)-propionic acid
  参考文献：
  名称：

  Antimicrobial β-peptoids by a block synthesis approach

  摘要：

  Antimicrobial peptides and their mimetics offer a potential new disinfective tool. beta-Peptoids (oligo-N-substituted beta-alanines) were synthesized and investigated for antimicrobial activity. A block approach whereby di- and tri-beta-peptoids were first prepared and then ligated via amide bond formation to synthesize larger beta-peptoids was developed. The beta-peptoids were found to possess moderate activity in an Escheridchia coli assay. (C) 2005 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2005.11.075