4-bromophenyl 4-methylphenyl disulphone | 141425-74-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-bromophenyl 4-methylphenyl disulphone
• 英文别名: 1-(4-Bromophenyl)sulfonylsulfonyl-4-methylbenzene
• CAS: 141425-74-3
• 化学式: C₁₃H₁₁BrO₄S₂
• 分子量: 375.264
• InChiKey: TZPXJPQUCDSKMV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  20
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  85
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  4-bromophenyl 4-methylphenyl disulphone 生成 对甲苯二硫醚
  参考文献：
  名称：

  BABU, J. RAMESH;BHATT, M. VIVEKANANDA, TETRAHEDRON LETT., 1986, 27, N 9, 1073-1074

  摘要：

  DOI：

文献信息

• New reagents 41. Reduction of sulphonyl chlorides and sulphoxideswith aluminum iodide
  作者：J. Ramesh Babau、M. Vivekananda Bhatt

  DOI：10.1016/s0040-4039(86)80051-x

  日期：1986.1

  Aluminium iodide reduces sulphonyl chlorides to disulphides and sulphoxides to sulphides under mild conditions in acetonitrile.

  碘化铝在温和的乙腈条件下将磺酰氯还原为二硫化物，将亚砜还原为硫化物。
• METHOD FOR PREPARING INDUCED PLURIPOTENCY STEM CELLS FROM MESENCHYMAL STEM CELLS BY USING PHLOROTANNIN FRACTION
  申请人：BBHC Co. Ltd.

  公开号：EP3147352A1

  公开（公告）日：2017-03-29

  The present invention relates to a medium composition for the dedifferentiation of induced pluripotency stem cells, containing a phlorotannin fraction extracted and isolated from one type of brown algae selected from the group consisting of Ecklonia cava, Dictyopteris prolifera, Dictyota coriacea, Sargassum horneri, Ishige okamurai and the like. In addition, the present invention relates to a method for preparing induced pluripotency stem cells by using the medium composition. Induced pluripotency stem cells can be safely, easily and effectively prepared by using mesenchymal stem cells by using the medium composition of the present invention, and the prepared induced pluripotency stem cells can be differentiated into various cells, and thus can be useful as a cell therapeutic agent.

  本发明涉及一种用于诱导多能干细胞去分化的培养基组合物，该培养基组合物含有从一种褐藻中提取和分离的绿单宁组分，该褐藻选自Ecklonia cava、Dictyopteris prolifera、Dictyota coriacea、Sargassum horneri、Ishige okamurai等。此外，本发明还涉及一种使用该培养基组合物制备诱导多能干细胞的方法。通过使用本发明的培养基组合物，可以安全、简便、有效地制备利用间充质干细胞制备的诱导多能干细胞，制备的诱导多能干细胞可以分化成各种细胞，因此可以作为细胞治疗剂使用。
• BABU, J. RAMESH;BHATT, M. VIVEKANANDA, TETRAHEDRON LETT., 1986, 27, N 9, 1073-1074
  作者：BABU, J. RAMESH、BHATT, M. VIVEKANANDA

  DOI：——

  日期：——