6-O-Tosyl-1-desoxy-1-acetylmercapto-2,3,4-tri-O-acetyl-β-D-glucopyranose | 100687-22-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 6-O-Tosyl-1-desoxy-1-acetylmercapto-2,3,4-tri-O-acetyl-β-D-glucopyranose
• 英文别名: [(2R,3R,4S,5R,6S)-4,5-diacetyloxy-6-acetylsulfanyl-2-[(4-methylphenyl)sulfonyloxymethyl]oxan-3-yl] acetate
• CAS: 100687-22-7
• 化学式: C₂₁H₂₆O₁₁S₂
• 分子量: 518.563
• InChiKey: MBSZWEVLCMXLPU-ADAARDCZSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  34
• 可旋转键数：
  12
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.52
• 拓扑面积：
  182
• 氢给体数：
  0
• 氢受体数：
  12

文献信息

• TARGETED NANOPARTICLES FOR CANCER DIAGNOSIS AND TREATMENT
  申请人：CHEN Jie

  公开号：US20100034735A1

  公开（公告）日：2010-02-11

  The invention provides modified gold nanoparticles that enable a non-invasive, real time, targeted cancer imaging-therapeutic in one step. After reaching the cancer targets, the designed targeted gold nanoparticles significantly enhance conventional treatment modalities at the cellular level. In this aspect the gold nanoparticles of the invention are modified to be bound to a Positron Emission Tomography (PET) tracer.