ethyl 3-[N-(3-ethoxy-3-oxopropyl)-4-(1,3,4-thiadiazol-2-yldiazenyl)anilino]propanoate | 1256742-52-5

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: ethyl 3-[N-(3-ethoxy-3-oxopropyl)-4-(1,3,4-thiadiazol-2-yldiazenyl)anilino]propanoate
• CAS: 1256742-52-5
• 化学式: C₁₈H₂₃N₅O₄S
• 分子量: 405.478
• InChiKey: RLEBSUPTFMDTDA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  28
• 可旋转键数：
  13
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.44
• 拓扑面积：
  135
• 氢给体数：
  0
• 氢受体数：
  10

反应信息

• 作为产物：
  描述：

  2-氨基-1,3,4-噻二唑 、 3,3'-(苯基氮二基)二丙酸二乙酯 在 硫酸 、 溶剂黄146 、 丙酸 、 sodium nitrite 、 乙酸酐 作用下， 反应 5.0h， 以70%的产率得到ethyl 3-[N-(3-ethoxy-3-oxopropyl)-4-(1,3,4-thiadiazol-2-yldiazenyl)anilino]propanoate
  参考文献：
  名称：

  The synthesis and development of a dual-analyte colorimetric sensor: Simultaneous estimation of Hg2+ and Fe3+

  摘要：

  The selectivity and sensitivity of a pH stable hetarylazo dye equipped with binding sites consisting of N S and N 0 combinations towards Hg2+ and Fe3+ over a large number of other cations including lanthanides is described Hg2+ and Fe3+ ions coordinate to the dye through N S binding site forming 2 1 and 1 1 complexes respectively Distinct naked-eye color changes for both Hg2+ (yellow to purple) and Fe3+ (yellow to red) were quantified for simultaneous estimation of these ions To further establish the binding and sensing phenomenon another analogous hetarylazo dye lacking N 0 combination was evaluated and found to give similar results For practical applicability in routine life very handy and ready-to-use paper strips coated with the dye have been prepared for the detection of Hg2+ just like the pH paper strips (C) 2010 Elsevier Ltd All rights reserved

  DOI：

  10.1016/j.dyepig.2010.07.012