(1S)-2-amino-1-(4-fluorophenyl)ethan-1-ol hydrochloride | 960204-65-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (1S)-2-amino-1-(4-fluorophenyl)ethan-1-ol hydrochloride
• 英文别名: (1S)-2-amino-1-(4-fluorophenyl)ethanol;hydrochloride
• CAS: 960204-65-3
• 化学式: C8H11ClFNO
• mdl: MFCD28064006
• 分子量: 191.63
• InChiKey: PNSJHCBYUNINNI-DDWIOCJRSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.61
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  46.2
• 氢给体数：
  3
• 氢受体数：
  3

文献信息

• Amido thiadiazole derivatives as NADPH oxidase inhibitors
  申请人：GENKYOTEX SUISSE SA

  公开号：US10130619B2

  公开（公告）日：2018-11-20

  The present invention is related to amino thiazole derivatives of Formula (I), pharmaceutical composition thereof and to their use for the treatment and/or prophylaxis of disorders or conditions related to Nicotinamide adenine dinucleotide phosphate oxidase (NADPH Oxidase).

  本发明涉及式（I）的氨基噻唑衍生物、其药物组合物及其用于治疗和/或预防与烟酰胺腺嘌呤二核苷酸磷酸氧化酶（NADPH 氧化酶）有关的紊乱或病症的用途。
• AMIDO THIADIAZOLE DERIVATIVES AS NADPH OXIDASE INHIBITORS
  申请人：GENKYOTEX SUISSE SA

  公开号：US20170348296A1

  公开（公告）日：2017-12-07

  The present invention is related to amino thiazole derivatives of Formula (I), pharmaceutical composition thereof and to their use for the treatment and/or prophylaxis of disorders or conditions related to Nicotinamide adenine dinucleotide phosphate oxidase (NADPH Oxidase).