2,6-Di(isothiocyanato)pyridin | 40479-93-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 2,6-Di(isothiocyanato)pyridin
• 英文别名: 2,6-diisothiocyanato-pyridine；2,6-Diisothiocyanatopyridine
• CAS: 40479-93-4
• 化学式: C₇H₃N₃S₂
• 分子量: 193.253
• InChiKey: STGSYFZRAQHZQC-UHFFFAOYSA-N

物化性质

• 熔点：
  54-55 °C(Solv: hexane (110-54-3))
• 沸点：
  393.1±27.0 °C(Predicted)
• 密度：
  1.30±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  102
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  2,6-二氨基吡啶 、 硫光气 以85%的产率得到
  参考文献：
  名称：

  NAGARAJAN K.; GOUD A. NAGANA; RAO V. RANGA; SHAH R. K.; SEN H. G.; DEB B.+, INDIAN J. PHARM. SCI., 48,(1986) N 3, 53-59

  摘要：

  DOI：

文献信息

• Electroplating additive for the deposition of a metal, a binary, ternary, quaternary or pentanary alloy of elements of group 11 (IB)-group 13 (IIIA)-group 16 (VIA)
  申请人：ATOTECH Deutschland GmbH

  公开号：EP2128903A1

  公开（公告）日：2009-12-02

  The invention relates to electroplating additives for the deposition of a group (11) (lB) metal/binary or ternary group (11) (IB)-group (13) (lIlA)/ternary, quaternary or pentanary group (11) (lB)-group (13) (lIlA)-group (16) (VIA) alloy on substrates useful for thin film solar cells. The additives have the general formula (A): wherein X1 and X2 may be the same or different and are selected from the group consisting of arylene and heteroarylene; FG1 and FG2 may be the same or different or are selected from the group consisting of -S(O)2OH, -S(O)OH, -COOH, -P(O)2OH and primary, secondary and tertiary amino groups and salts and esters thereof; R is selected from the group consisting of alkylene, arylene or heteroarylene and n and m are integers from 1 to 5.

  本发明涉及用于在薄膜太阳能电池基板上沉积(11)(lB)族金属/二元或三元(11)(IB)-(13)(lIlA)族/三元、四元或五元(11)(lB)-(13)(lIlA)-(16)(VIA)族合金的电镀添加剂。添加剂的通式为 (A)： 其中 X1 和 X2 可以相同或不同，并且选自由芳基和杂芳基组成的组；FG1 和 FG2 可以相同或不同，或者选自由-S(O)2OH、-S(O)OH、-COOH、-P(O)2OH 和伯、仲、叔氨基及其盐和酯组成的组；R 选自由亚烷基、芳基或杂芳基组成的组，n 和 m 是 1 至 5 的整数。
• RAAV WITH CHEMICALLY MODIFIED CAPSID
  申请人：CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)

  公开号：US20210205467A1

  公开（公告）日：2021-07-08

  The invention is directed to the field of gene therapy, i.e. gene delivery into target cells, tissue, organ and organism, and more particularly to gene delivery via viral vectors. The inventors showed that it is possible by chemical coupling to modulate the coupling of a ligand in the surface of the capsid of AAV, for example AAV2 and AAV3b. In particular, the present invention relates to a recombinant Adeno-Associated Virus (rAAV) vector particle having at least one primary amino group contained in the capsid proteins, chemically coupled with at least one ligand L, wherein coupling of said ligand L is implemented through a bond comprising a —CSNH— bond and an optionally substituted aromatic moiety. Particularly, the inventors tested the chemical coupling of mannose ligand on AAV2 for subretinally injection to rats. The present invention further relates to a method for chemically coupling an Adeno-Associated Virus (AAV) vector particle with at least one ligand L and to a Recombinant Adeno-Associated Virus (rAAV) vector particle obtained by said method as well as a pharmaceutical composition comprising it and their corresponding medical use.
• US5310916A
  申请人：——

  公开号：US5310916A

  公开（公告）日：1994-05-10