4-皮考啉月桂基硫酸酯盐 | 84176-63-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 中文名称: 4-皮考啉月桂基硫酸酯盐
• 英文名称: 4-Methylpyridinium decyl sulfate
• 英文别名: dodecyl hydrogen sulfate;4-methylpyridine
• CAS: 84176-63-6
• 化学式: C18H33NO4S
• 分子量: 359.5
• InChiKey: YLATXFLJXBPIPT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.12
• 重原子数：
  24
• 可旋转键数：
  12
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.72
• 拓扑面积：
  84.9
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• Immunological adjuvant compositions
  申请人：Ott S. Gary

  公开号：US20050123599A1

  公开（公告）日：2005-06-09

  The present invention is directed to novel adjuvant compositions, which target the cellular and/or humoral arms of immunity. According to an embodiment of the invention, an oil-in-water adjuvant composition is provided that comprises: (a) water; (b) a metabolizable oil comprising at least one branched or unbranched long-chain hydrocarbon moiety; (c) a steroid; and (d) a saponin.

  本发明涉及新型佐剂组合物，其针对细胞和/或体液免疫方面。根据本发明的一种实施方式，提供了一种油水佐剂组合物，其包括：(a)水；(b)一种可代谢的油，其中至少包含一种支链或直链长链碳氢基团；(c)一种类固醇；以及(d)一种皂苷。
• Hydrophilic microplates for vertical beam photometry
  申请人：Molecular Devices Corporation

  公开号：EP0290125A2

  公开（公告）日：1988-11-09

  A microtiter plate prepared from a hydrophobic plastic is rendered more hydrophilic by treatment of the surfaces of the wells of the microplate prior to use. The resulting plates are particularly useful in vertical beam photometry.

  使用疏水性塑料制备的微孔板，在使用前可通过对微孔板的孔表面进行处理来增加其亲水性。这种微孔板尤其适用于垂直光束光度测量。
• Cleaning using cyclodextrin
  申请人：MICROGENICS CORPORATION

  公开号：EP0301847A1

  公开（公告）日：1989-02-01

  A method of removing a surfactant from an en­vironment containing the surfactant is provided, which comprises contacting the surfactant with an amount of cyclodextrin sufficient to bind all or part of the sur­factant, thereby providing a cyclodextrin-bound surfac­tant, and separating the cyclodextrin-bound surfactant from the environment.

  提供了一种从含有表面活性剂的环境中去除表面活性剂的方法，该方法包括将表面活性剂与一定量的环糊精接触，环糊精的量足以结合全部或部分表面活性剂，从而提供环糊精结合的表面活性剂，并将环糊精结合的表面活性剂从环境中分离出来。
• Reagent composition comprising enzyme donor
  申请人：MICROGENICS CORPORATION

  公开号：EP0348173A2

  公开（公告）日：1989-12-27

  Normally interacting reagents are both present in a liquid single reagent but complex formation is inhibited using a surfactant; the inhibition is reversed in the presence of analyte by adding a cyclodextrin. The invention finds particular use in diagnostic immuno­assays.

  通常情况下，相互作用的试剂都存在于液体单一试剂中，但使用表面活性剂可抑制复合物的形成；在分析物存在的情况下，加入环糊精可逆转抑制作用。本发明特别适用于诊断性免疫测定。
• Adjuvant formulation comprising a submicron oil droplet emulsion
  申请人：CHIRON CORPORATION

  公开号：EP0399843A2

  公开（公告）日：1990-11-28

  An adjuvant composition, comprising a metabolizable oil and an emulsifying agent, wherein the oil and the detergent are present in the form of an oil-in-water emulsion having oil droplets substantially all of which are less than 1 micron in diameter. In preferred embodiments, the emulsifying agent is also an immunostimulating agent, such as a lipophilic muramyl peptide. Alternatively, an immunostimulating agent separate from the emulsifying agent can be used.

  一种佐剂组合物，由可代谢的油和乳化剂组成，其中油和洗涤剂以水包油乳液的形式存在，其油滴的直径基本上都小于 1 微米。在优选的实施方案中，乳化剂也是一种免疫刺激剂，例如亲脂性μramyl 肽。或者，也可以使用与乳化剂分开的免疫刺激剂。