| 1407686-86-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 蒽
• CAS: 1407686-86-5
• 化学式: C₁₆H₁₃ClN₂O₂
• 分子量: 300.744
• InChiKey: XTPCTYVRBILZOC-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  5-carboxymethyeleneoxyphenyl-10,15,20-tris(4-methoxyphenyl)porphyrin 、 在 1-羟基苯并三唑 、 盐酸-N-乙基-Nˊ-(3-二甲氨基丙基)碳二亚胺 作用下， 以 二氯甲烷 为溶剂， 反应 15.75h， 以50%的产率得到
  参考文献：
  名称：

  Facile Synthesis of a Phototoxic Monofunctionalized Tetraarylporphyrin as Scaffold for Porphyrin-Quinone Conjugates

  摘要：

  A new carboxy-monofunctionalized tertraarylporphyrin has been tested for cytotoxicity toward OV2008 human ovarian cancer cells. This compound acutely inhibits growth of ovarian cancer cells upon exposure to ambient light while suppresses long-term clonogenic survival of cells under both dark and light stimulated conditions. Because of the variable length of the linkage between the anthraquinone and porphyrin moieties, the synthesized monocarboxylated porphyrin presents a versatile scaffold for fine-tuning of the photoelectron transfer in the quinone-porphyrin conjugate. To demonstrate its synthetic value, we converted the carboxy derivative to its amino counterpart.

  DOI：

  10.1080/00397911.2011.594546