(2E)-2-hydroxyimino-2-(4-methoxyphenyl)-N-propan-2-ylacetamide | 61365-40-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (2E)-2-hydroxyimino-2-(4-methoxyphenyl)-N-propan-2-ylacetamide
• CAS: 61365-40-0
• 化学式: C₁₂H₁₆N₂O₃
• 分子量: 236.271
• InChiKey: WSABRFLEWGTFQW-SDNWHVSQSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  17
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  70.9
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  2-(4-methoxyphenyl)-2-oxo-N-propan-2-ylacetamide 在 盐酸羟胺 、 碳酸氢钠 作用下， 以 异丙醇 为溶剂， 生成 (2E)-2-hydroxyimino-2-(4-methoxyphenyl)-N-propan-2-ylacetamide
  参考文献：
  名称：

  Nocardicin A，一种新型的单环β-内酰胺类抗生素II。诺卡霉素A和B的结构测定。

  摘要：

  根据光谱和化学证据，诺卡氏菌菌株生产的新型单环β-内酰胺抗生素诺卡氏菌素A和B的结构分别确定为1和2。它们是具有相对较高抗菌活性的单环β-内酰胺抗生素的首例，并且在化学和生物学上与青霉素和头孢菌素有关。

  DOI：

  10.7164/antibiotics.29.890

文献信息

• FUNGICIDAL HYDROXIMOYL-HETEROCYCLES DERIVATIVES
  申请人：Bayer CropScience AG

  公开号：EP2519502A2

  公开（公告）日：2012-11-07
• FUNGICIDE HYDROXIMOYL-HETEROCYCLES DERIVATIVES
  申请人：Beier Christian

  公开号：US20130040993A1

  公开（公告）日：2013-02-14

  The present invention relates to hydroximoyl-heterocycle derivatives, their process of preparation, their use as fungicide active agents, particularly in the form of fungicide compositions, and methods for the control of phytopathogenic fungi, notably of plants, using these compounds or compositions.
• US9000012B2
  申请人：——

  公开号：US9000012B2

  公开（公告）日：2015-04-07
• [EN] FUNGICIDE HYDROXIMOYL-HETEROCYCLES DERIVATIVES<br/>[FR] DÉRIVÉS HYDROXIMOYL-HÉTÉROCYCLES FONGICIDES
  申请人：BAYER CROPSCIENCE AG

  公开号：WO2011080254A2

  公开（公告）日：2011-07-07

  The present invention relates to hydroximoyl-heterocycle derivatives, their process of preparation, their use as fungicide active agents, particularly in the form of fungicide compositions, and methods for the control of phytopathogenic fungi, notably of plants, using these compounds or compositions.
• Nocardicin A, a new monocyclic .BETA.-lactam antibiotic. II. Structure determination of nocardicins A and B.
  作者：MASASHI HASHIMOTO、TADAAKI KOMORI、TAKASHI KAMIYA

  DOI：10.7164/antibiotics.29.890

  日期：——

  The structures of nocardicins A and B, novel monocyclic beta-lactam antibiotics produced by a strain of Nocardia, have been established as 1 and 2, respectively, on the basis of spectroscopic and chemical evidence. They are the first examples of monocyclic beta-lactam antibiotics possessing relatively high antimicrobial activity, and are stereochemically and biologically related to penicillins and

  根据光谱和化学证据，诺卡氏菌菌株生产的新型单环β-内酰胺抗生素诺卡氏菌素A和B的结构分别确定为1和2。它们是具有相对较高抗菌活性的单环β-内酰胺抗生素的首例，并且在化学和生物学上与青霉素和头孢菌素有关。