ethyl 2-[2-(2-naphthyl)-2-oxoethyl]-3-(1,1,1-triphenyl-λ⁵-phosphanylidene)succinate | 1156461-23-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: ethyl 2-[2-(2-naphthyl)-2-oxoethyl]-3-(1,1,1-triphenyl-λ⁵-phosphanylidene)succinate
• CAS: 1156461-23-2
• 化学式: C₃₈H₃₅O₅P
• 分子量: 602.667
• InChiKey: ITDNCVFTQMVZHU-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  在 basic alumina powder 作用下， 反应 2.0h， 生成 ethyl 2-[2-(2-naphthyl)-2-oxoethyl]-3-(1,1,1-triphenyl-λ⁵-phosphanylidene)succinate
  参考文献：
  名称：

  Synthesis of Sterically Congested Stabilized Phosphorus Ylides from Acetylenic Esters, 4,4,4-Trifluoro-1-(2naphthyl)-1,3-butanedione, and Triphenylphosphine

  摘要：

  Protonation of the highly reactive 1:1 intermediates, produced in the reaction between triphenylphosphine and dialkyl acetylenedicarboxylates, by 4,4,4-trifluoro-1-(2-naphthyl)-1,3-butanedione leads to vinyltriphenylphosphonium salts, which undergo Michael addition reaction with conjugate base to produce corresponding sterically congested fluorine-containing phosphorus ylides. Basic alumina powder was found to catalyze conversion of the sterically congested fluorine-containing phosphorus ylides to dialkyl 2-[2-(2-naphthyl)-2-oxoethyl]-3-(1,1,1-triphenyl-lambda(5)-phosphanylidene)succinates in solvent-free conditions under microwave (0.9 KW, 3 min) and thermal (25 degrees C, 120 min.) conditions.

  DOI：

  10.1080/10426500701693420