Methyl-N-(3-carbamoylphenyl)carbamat | 90868-34-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Methyl-N-(3-carbamoylphenyl)carbamat
• 英文别名: 3-methoxycarbonylamino-benzoic acid amide；(3-Carbamoyl-phenyl)-carbamidsaeure-methylester；3-Methoxycarbonylamino-benzoesaeure-amid；methyl N-(3-carbamoylphenyl)carbamate
• CAS: 90868-34-1
• 化学式: C₉H₁₀N₂O₃
• 分子量: 194.19
• InChiKey: JWJMLGIKTHRYHG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  14
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  81.4
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  N-(3-氰基苯基)氨基甲酸甲酯 在 双氧水 作用下， 生成 Methyl-N-(3-carbamoylphenyl)carbamat
  参考文献：
  名称：

  Blanksma; Petri, Recueil des Travaux Chimiques des Pays-Bas, 1947, vol. 66, p. 369

  摘要：

  DOI：

文献信息

• NANOSTRUCTURED GELS CAPABLE OF CONTROLLED RELEASE OF ENTRAPPED AGENTS
  申请人：The Brigham and Women's Hospital, Inc.

  公开号：US20170000888A1

  公开（公告）日：2017-01-05

  Self-assembled gel compositions including a gelator, e.g., an enzyme-cleavable gelator, e.g., having a molecular weight of 2500 or less, are described. The self-assembled gel compositions can encapsulate one or more agents. Methods of making the self-assembled gel compositions, and methods of drug delivery using the self-assembled gel compositions are also described.

  描述了包括凝胶剂的自组装凝胶组合物，例如，一种酶可切割的凝胶剂，例如，具有分子量不超过2500的凝胶剂。这些自组装凝胶组合物可以包裹一个或多个药剂。还描述了制备这些自组装凝胶组合物的方法，以及使用这些自组装凝胶组合物进行药物传递的方法。
• Nanostructured gels capable of controlled release of encapsulated agents
  申请人：The Brigham and Women's Hospital, Inc.

  公开号：US10675351B2

  公开（公告）日：2020-06-09

  Self-assembled gel compositions including a gelator, e.g., an enzyme-cleavable gelator, e.g., having a molecular weight of 2500 or less, are described. The self-assembled gel compositions can encapsulate one or more agents. Methods of making the self-assembled gel compositions, and methods of drug delivery using the self-assembled gel compositions are also described.

  本文描述了自组装凝胶组合物，其中包括凝胶剂，如分子量为 2500 或更小的可酶解凝胶剂。自组装凝胶组合物可以封装一种或多种药剂。还描述了自组装凝胶组合物的制造方法和使用自组装凝胶组合物的给药方法。
• NANOSTRUCTURED GELS CAPABLE OF CONTROLLED RELEASE OF ENCAPSULATED AGENTS
  申请人：The Brigham and Women's Hospital, Inc.

  公开号：EP3412279B1

  公开（公告）日：2021-02-17
• Nanostructured Gels Capable of Controlled Release of Encapsulated Agents
  申请人：Karp Jeffrey M.

  公开号：US20130280334A1

  公开（公告）日：2013-10-24

  Self-assembled gel compositions including a gelator, e.g., an enzyme-cleavable gelator, e.g., having a molecular weight of 2500 or less, are described. The self-assembled gel compositions can encapsulate one or more agents. Methods of making the self-assembled gel compositions, and methods of drug delivery using the self-assembled gel compositions are also described.
• US5089633A
  申请人：——

  公开号：US5089633A

  公开（公告）日：1992-02-18