| 1033054-07-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• CAS: 1033054-07-7
• 化学式: C₁₁H₉BrN₂
• 分子量: 249.11
• InChiKey: CKJFBQAMEWNVQF-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  在 silver hexafluoroantimonate 作用下， 以 二氯甲烷 为溶剂， 反应 5.0h， 以45%的产率得到
  参考文献：
  名称：

  Silver(I)-Catalyzed Facile Synthesis of Pyrazoles From Propargyl N-Sulfonylhydrazones

  摘要：

  A silver(I)-catalyzed facile formation of pyrazoles from propargyl N-sulfonylhydrazones has been disclosed. During the reaction, a migration of sulfonyl groups (Ts, Ms) was observed. Good functional group compatibility was observed under mild reaction conditions (at room temperature for 3-5 h). This methodology allows for the efficient and regioselective synthesis of 1,3- and 1,5-disubstituted and 1,3,5-trisubstituted pyrazoles.

  DOI：

  10.1021/jo800663g