1H-Imidazol-2-amine, N-(2-chloro-3,5-dimethoxyphenyl)-4,5-dihydro- | 573704-42-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1H-Imidazol-2-amine, N-(2-chloro-3,5-dimethoxyphenyl)-4,5-dihydro-
• 英文别名: N-(2-chloro-3,5-dimethoxyphenyl)-4,5-dihydro-1H-imidazol-2-amine
• CAS: 573704-42-4
• 化学式: C₁₁H₁₄ClN₃O₂
• 分子量: 255.7
• InChiKey: PTEIKOHMOSEBER-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  17
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  54.9
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• 2'-Halo-3',5'-dialkoxyphen-1'-yl-imino-2-imidazolidine and the use thereof as a drug
  申请人：Boehringer Ingelheim Pharma KG

  公开号：US20030162822A1

  公开（公告）日：2003-08-28

  The present invention relates to 2′-halo-3′,5′-dialkoxyphen-1′-yl-imino-2-imidazolidine, the tautomeric 2′-halo-3′,5′-dialkoxyanilino-2-imidazoline and/or the pharmacologically acceptable salts thereof and their use as pharmaceutical compositions.

  本发明涉及2'-卤代-3',5'-二烷氧基苯-1'-基亚胺-2-咪唑啉，其互变异构体2'-卤代-3',5'-二烷氧基苯胺基-2-咪唑啉和/或其药理学上可接受的盐，并将其用作药物组合物。
• 2'-Halo-3',5'-dialkoxyphen-1'-yl-imino-2-imidazolidine derivatives and the use thereof for the treatment of urinary incontinence
  申请人：Boehringer Ingelheim Pharma GmbH & Co.KG

  公开号：EP1333028A1

  公开（公告）日：2003-08-06

  The present invention relates to 2'-halo-3',5'-dialkoxyphen-1'-yl-imino-2-imidazolidine, the tautomeric 2'-halo-3',5'-dialkoxyanilino-2-imidazoline and/or the pharmacologically acceptable salts thereof and their use as pharmaceutical compositions, in the treatment of urinary incontinence.

  本发明涉及2'-卤代-3',5'-二烷氧基苯-1'-基-亚胺-2-咪唑啉，其互变异构体2'-卤代-3',5'-二烷氧基苯胺基-2-咪唑啉和/或其药理学上可接受的盐，以及它们作为药物组合物在治疗尿失禁中的应用。
• 2'-HALO-3',5'-DIALKOXYPHEN-1'-YL-IMINO-2-IMIDAZOLIDINE DERIVATIVES AND THE USE THEREOF FOR THE TREATMENT OF URINARY INCONTINENCE
  申请人：Boehringer Ingelheim Pharma GmbH & Co. KG

  公开号：EP1472231A1

  公开（公告）日：2004-11-03
• US6703409B2
  申请人：——

  公开号：US6703409B2

  公开（公告）日：2004-03-09
• [EN] 2'-HALO-3',5'-DIALKOXYPHEN-1'-YL-IMINO-2-IMIDAZOLIDINE DERIVATIVES AND THE USE THEREOF FOR THE TREATMENT OF URINARY INCONTINENCE<br/>[FR] DERIVES DE 2'-HALO-3',5'-DIALCOXYPHEN-1'-YL-IMINO-2-IMIDAZOLIDINE ET LEUR UTILISATION POUR TRAITER L'INCONTINENCE URINAIRE
  申请人：BOEHRINGER INGELHEIM PHARMA

  公开号：WO2003064398A1

  公开（公告）日：2003-08-07

  The present invention relates to 2'-halo-3',5'-dialkoxyphen-1'-yl-imino-2- imidazolidine, the tautomeric 2'-halo-3',5'-dialkoxyanilino-2-imidazoline and/or the pharmacologically acceptable salts thereof and their use as pharmaceutical compositions, in the treatment of urinary incontinence (I).