1,2-Bis-(5-oxo-3-methoxycarbonyl-pyrrolidino)-ethan | 106736-61-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯烷类
• 英文名称: 1,2-Bis-(5-oxo-3-methoxycarbonyl-pyrrolidino)-ethan
• 英文别名: 5,5'-dioxo-1,1'-ethane-1,2-diyl-bis-pyrrolidine-3-carboxylic acid dimethyl ester；Methyl 1-[2-(4-methoxycarbonyl-2-oxopyrrolidin-1-yl)ethyl]-5-oxopyrrolidine-3-carboxylate
• CAS: 106736-61-2
• 化学式: C₁₄H₂₀N₂O₆
• 分子量: 312.323
• InChiKey: VUWHSJNNIOUMNX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.6
• 重原子数：
  22
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  93.2
• 氢给体数：
  0
• 氢受体数：
  6

文献信息

• FILM FORMING COATING COMPOSITIONS CONTAINING CARBOXAMIDE COALESCING SOLVENTS AND METHODS OF USE
  申请人：Luebke Gary

  公开号：US20130143986A1

  公开（公告）日：2013-06-06

  A film may be formed from film forming compositions which comprise at least one carboxamide based coalescing solvent. These coalescing solvents impart equivalent or improved wet-scrub resistance, block resistance, gloss, dirt pick-up resistance and leveling characteristics to the films on a substrate, without contributing to total VOC levels, when replacing conventional coalescing solvents. The present invention also includes a method for forming a film comprising applying a film forming composition comprising polyunsaturated reactive carboxamides to a substrate and curing the film under ambient conditions. The coalescing carboxamide solvents are suitable for paint, latex based caulk, adhesives and floor care applications.

  可以使用至少一种基于羧酰胺的共溶剂来制备膜形成组合物，从而形成一种电影。当取代传统的共溶剂时，这些共溶剂可以赋予膜在基材上等效或改善的耐湿擦洗性、阻塞性、光泽度、防尘性和平整特性，而不会对总挥发性有所贡献。本发明还包括一种方法，用于形成膜，包括将含有多不饱和反应性羧酰胺的膜形成组合物涂覆在基材上，并在环境条件下固化膜。这些共溶剂适用于涂料、乳胶基密封胶、粘合剂和地面保养应用。
• Pyrrolidone derivatives, oligomers and polymers
  申请人：NanoSynthons LLC

  公开号：US10968176B2

  公开（公告）日：2021-04-06

  Simple organic structures, organic/inorganic polymers, and other substrates have been made, all of which have at least one pyrrolidone moiety present, and found to exhibit low toxicity, low complement activation features and may be used to reduce protein interactions with drug conjugates while enhancing in vivo residency times for these conjugates when used as an injectable composition; thus these compounds can be used as substitutes for PEG in PEGylation. Surprisingly, these compounds also exhibit unique intrinsic fluorescence (IF) or non-traditional fluorescence (NTF) properties that currently cannot be explained by traditional photochemistry and fluorescence paradigms are described. These compounds have a variety of applications such as in cellular imaging, gene transfection, bio-diagnostics, biosensing, fluorescence directed surgical resections, drug delivery, forensics, environmental diagnostics, mineral/gemstone characterization, counterfeit goods detection, tracer studies related to liquid/water flow, oil field enhancements and diagnostics, prevention of photo-bleaching, and LED display enhancements and others.

  我们已经制备出了简单的有机结构、有机/无机聚合物和其他基质，所有这些基质都至少含有一个吡咯烷酮分子，并发现它们具有低毒性、低补体激活特性，可用于减少蛋白质与药物共轭物的相互作用，同时在用作注射组合物时可提高这些共轭物在体内的驻留时间；因此，这些化合物可在 PEG 化过程中用作 PEG 的替代品。令人惊奇的是，这些化合物还表现出独特的本征荧光（IF）或非传统荧光（NTF）特性，而这些特性目前还无法用传统的光化学和荧光范式来解释。这些化合物有多种应用，如细胞成像、基因转染、生物诊断、生物传感、荧光引导手术切除、给药、法医、环境诊断、矿物/宝石表征、假冒商品检测、与液体/水流有关的示踪研究、油田增强和诊断、防止光漂白、LED 显示屏增强等。
• COMPOSITION COMPRISING AT LEAST ONE 2-PYRROLIDONE FUNCTIONALIZED WITH AN ESTER OR AMIDE RADICAL, AND AT LEAST ONE PIGMENT OR DIRECT DYE, FOR DYEING KERATIN MATERIALS
  申请人：L'Oréal

  公开号：EP2579841B1

  公开（公告）日：2016-09-14
• PYRROLIDONE DERIVATIVES, OLIGOMERS AND POLYMERS
  申请人：NanoSynthons LLC

  公开号：US20190352258A1

  公开（公告）日：2019-11-21

  Simple organic structures, organic/inorganic polymers, and other substrates have been made, all of which have at least one pyrrolidone moiety present, and found to exhibit low toxicity, low complement activation features and may be used to reduce protein interactions with drug conjugates while enhancing in vivo residency times for these conjugates when used as an injectable composition; thus these compounds can be used as substitutes for PEG in PEGylation. Surprisingly, these compounds also exhibit unique intrinsic fluorescence (IF) or non-traditional fluorescence (NTF) properties that currently cannot be explained by traditional photochemistry and fluorescence paradigms are described. These compounds have a variety of applications such as in cellular imaging, gene transfection, bio-diagnostics, biosensing, fluorescence directed surgical resections, drug delivery, forensics, environmental diagnostics, mineral/gemstone characterization, counterfeit goods detection, tracer studies related to liquid/water flow, oil field enhancements and diagnostics, prevention of photo-bleaching, and LED display enhancements and others.
• US8771376B2
  申请人：——

  公开号：US8771376B2

  公开（公告）日：2014-07-08