(+/-)-linderaspirone A | 1235126-49-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (+/-)-linderaspirone A
• 英文别名: (8S,16S)-2,3,6,11,12,14-Hexamethoxy-8,16-diphenyldispiro[4.3.4.3]hexadeca-2,6,11,14-tetraene-1,4,10,13-tetrone；(6S,7E,14S,15E)-2,3,8,11,12,16-hexamethoxy-6,14-diphenyldispiro[4.3.49.35]hexadeca-2,7,11,15-tetraene-1,4,10,13-tetrone
• CAS: 1235126-49-4
• 化学式: C₃₄H₃₂O₁₀
• 分子量: 600.622
• InChiKey: OASRMBZSJNAYKB-PPNOQCFFSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  44
• 可旋转键数：
  8
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  124
• 氢给体数：
  0
• 氢受体数：
  10

反应信息

• 作为产物：
  描述：

  Methyllinderone 在 偶氮二异丁腈 作用下， 以 甲苯 为溶剂， 反应 20.0h， 以54%的产率得到(+/-)-linderaspirone A
  参考文献：
  名称：

  One-step biomimetic synthesis of (±)-linderaspirone A and (±)-bi-linderone

  摘要：

  A one-step biomimetic synthesis of racemic linderspirone and bi-liderone from methyllinderone has been achieved, which probably reflects the biosynthesis of the natural products. There are few naturally occurring substances that appear to be formed by a [4+4] or [4+2] cycloaddition. We proposed that the [4+4] dimerization of methyllinderone proceeds via a stepwise mechanism involving a diradical intermediate. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2011.03.081

文献信息

• One-step biomimetic synthesis of (±)-linderaspirone A and (±)-bi-linderone
  作者：Gang-Qiang Wang、Kun Wei、Lin Zhang、Tao Feng、Fei Wang、Qiu-An Wang、Ji-Kai Liu

  DOI：10.1016/j.tetlet.2011.03.081

  日期：2011.5

  A one-step biomimetic synthesis of racemic linderspirone and bi-liderone from methyllinderone has been achieved, which probably reflects the biosynthesis of the natural products. There are few naturally occurring substances that appear to be formed by a [4+4] or [4+2] cycloaddition. We proposed that the [4+4] dimerization of methyllinderone proceeds via a stepwise mechanism involving a diradical intermediate. (C) 2011 Elsevier Ltd. All rights reserved.