(2R,3R,4R,5S)-6-(5-(9H-carbazol-9-yl)-5-oxopentyloxyimino)hexane-1,2,3,4,5-pentayl pentaacetate | 1101207-35-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 四吡咯及其衍生物
• 英文名称: (2R,3R,4R,5S)-6-(5-(9H-carbazol-9-yl)-5-oxopentyloxyimino)hexane-1,2,3,4,5-pentayl pentaacetate
• CAS: 1101207-35-5
• 化学式: C₃₃H₃₈N₂O₁₂
• 分子量: 654.671
• InChiKey: XSROWOHHJDDONR-ZGDUIDSNSA-N

反应信息

• 作为产物：
  描述：

  (11S,12R,13R,14R)-6-(3-(9H-carbazol-9-yl)-3-oxopropyl)-4-thioxo-3,8-dioxa-5-thia-9-azapentadec-9-ene-11,12,13,14,15-pentayl pentaacetate 在 偶氮二异丁腈 、 次磷酸 、 三乙胺 作用下， 以 1,4-二氧六环 、 水 为溶剂， 以24%的产率得到(2R,3R,4R,5S)-6-(5-(9H-carbazol-9-yl)-5-oxopentyloxyimino)hexane-1,2,3,4,5-pentayl pentaacetate
  参考文献：
  名称：

  A versatile radical based approach to O-alkylated hydroxylamines and oximes

  摘要：

  O-Alkylhydroxylamines, often used for the preparation of bioconjugates, can be readily obtained by radical addition to suitable O-alkenylhydroxylamine derivatives. In the case of N-Boc-O-allylhydroxylamine, the addition is unexpectedly followed by elimination resulting in an overall allylation of the radical species. (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2008.08.113