(Et4-ethylenediamine)palladium(II)(H2O)2(2+) | 137596-44-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯烷类
• 英文名称: (Et4-ethylenediamine)palladium(II)(H2O)2(2+)
• CAS: 137596-44-2
• 化学式: C₁₀H₂₈N₂O₂Pd
• 分子量: 314.765
• InChiKey: KHYMZLVYOAMKBM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
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• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为反应物：
  描述：

  barium ribose 5'-monophosphate 、 (Et4-ethylenediamine)palladium(II)(H2O)2(2+) 以 水 为溶剂， 生成 aqua(N,N,N',N'-tetraethylethylenediamine)palladim(II)(ribose 5'-monophosphate)
  参考文献：
  名称：

  Hohmann, Heribert; Hellquist, Björn; Van Eldik, Rudi, Inorganic Chemistry, 1992, vol. 31, # 6, p. 1090 - 1095

  摘要：

  DOI：

文献信息

• Effect of steric hindrance on kinetic and equilibrium data for substitution reactions of diaqua(N-substituted ethylenediamine)palladium(II) with chloride in aqueous solution
  作者：H. Hohmann、B. Hellquist、R. van Eldik

  DOI：10.1016/s0020-1693(00)80912-3

  日期：1991.10

  Abstract Kinetic and thermodynamic data are reported for the complex formation reactions: Pd(R4en)(H2O)22+Cl− Pd(R4en)(H2O)Cl++H2O and Pd(R4en)(H2O)Cl++Cl− Pd(R4en)Cl2+H2O, as a function of steric hindrance for RMe and Et. The reported rate constants for these reactions decrease drastically on increasing the steric hindrance. These findings along with strongly negative △S≠ values support the operation

  摘要报道了复杂形成反应的动力学和热力学数据：Pd（R4en）（H2O）22 + Cl- Pd（R4en）（ ）Cl ++ 和Pd（R4en）（ ）Cl ++ Cl− Pd（ R4en）Cl2 + ，是RMe和Et的位阻的函数。这些反应的报道的速率常数随着位阻的增加而急剧下降。这些发现以及强烈的负△S≠值支持了缔合反应机理的运行。报告了络合物形成的值和酸解离常数，从中可以构筑形态图。参照未取代的en系统和cis-Pt（NH3）2（ ）22+物种的相应数据讨论了所有结果。
• Mechanistic information on the reaction of model palladium(II) complexes with purine nucleosides and 5′-nucleotides in reference to the antitumor activity of related platinum complexes
  作者：M. Shoukry、H. Hohmann、R. van Eldik

  DOI：10.1016/s0020-1693(00)92360-0

  日期：1992.8

  The reaction of Pd(Me,en)Cl2 (Me4en=NNN',N'-tetramethylethylenediamine) with inosine and 5'-inosine monophosphate was studied as a function of chloride concentration and pH. Evidence for the formation of a 1:1 complex with these nucleophiles is presented, and the kinetic data indicate that Pd(Me4en)(Cl)H2O+ is the only reactive species under the selected experimental conditions. The results are compared to earlier data for the reactions of Pd(R4en)(H2O)22+ (R = H, Me, Et) with a series of nucleosides and 5'-nucleotides. The dependencies studied in this investigation allow some tentative extrapolations to conditions relevant for the antitumor activity of related Pt(II) complexes.