3-Methyl-4-(phenylhydrazono)-1-phthalazyl-2-pyrazolin-5-one | 132576-93-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氮杂萘
• 英文名称: 3-Methyl-4-(phenylhydrazono)-1-phthalazyl-2-pyrazolin-5-one
• CAS: 132576-93-3
• 化学式: C₁₈H₁₄N₆O
• 分子量: 330.349
• InChiKey: VMHZUTQHWHXDCI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.82
• 重原子数：
  25.0
• 可旋转键数：
  3.0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  82.84
• 氢给体数：
  1.0
• 氢受体数：
  6.0

反应信息

• 作为产物：
  描述：

  1-hydrazinophthalazine 、 3-oxo-2-(phenylhydrazono)butyric acid ethyl ester 以 溶剂黄146 为溶剂， 反应 6.0h， 以55%的产率得到3-Methyl-4-(phenylhydrazono)-1-phthalazyl-2-pyrazolin-5-one
  参考文献：
  名称：

  Jain; Shukla, Journal of the Indian Chemical Society, 1990, vol. 67, # 7, p. 575 - 576

  摘要：

  DOI：

文献信息

• Versatile ligational behavior of azopyrazolone derived from hydralazine
  作者：Susannah Seth、K.K. Aravindakshan

  DOI：10.1080/00958972.2012.675431

  日期：2012.5.10

  Five complexes of 3-methyl-4 -(phenylhydrazono)-1-phthalazinyl-2-pyrazolin-5-one (LH) were synthesized. The ligand and complexes were characterized using elemental analyses and various analytical techniques such as IR, UV, NMR, mass spectra, magnetic susceptibility measurements, and thermal decomposition studies such as TG/DTG. The geometries of the complexes with special emphasis on the versatile ligational behavior of LH are discussed. All five complexes have octahedral geometry. In four of the complexes [M(LH)Cl-3] where M = Fe(III)/Cr(III) and [M(LH)(OAc)(2)H2O] and M = Cu(II)/Ni(II), the ligand was neutral and tridentate. Another copper complex [CuL(OAc)(H2O)(2)] in which the ligand is tridentate, mono-anionic one was also obtained in an excess of aqueous solution. Antifungal studies of the compounds are also carried out.