2-(2-Furyl)imidazo<4,5-b>phenazin | 34972-26-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氮杂萘
• 英文名称: 2-(2-Furyl)imidazo<4,5-b>phenazin
• 英文别名: 2-furan-2-yl-1H-imidazo[4,5-b]phenazine；2-(furan-2-yl)-1H-imidazo[4,5-b]phenazine
• CAS: 34972-26-4
• 化学式: C₁₇H₁₀N₄O
• 分子量: 286.293
• InChiKey: CTSHPLPNNNCUST-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.92
• 重原子数：
  22.0
• 可旋转键数：
  1.0
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  67.6
• 氢给体数：
  1.0
• 氢受体数：
  4.0

反应信息

• 作为反应物：
  描述：

  2-(2-Furyl)imidazo<4,5-b>phenazin 、 碘甲烷 在 氢氧化钾 作用下， 以 乙醇 为溶剂， 生成 2-furan-2-yl-1-methyl-1H-imidazo[4,5-b]phenazine
  参考文献：
  名称：

  2-（2-呋喃基）-和2- [β-（2-呋喃基）乙烯基]咪唑并[4,5-b]吩嗪的合成与转化

  摘要：

  DOI：

  10.1007/bf00479965
• 作为产物：
  描述：

  邻苯二胺 在 盐酸 、 iron(III) chloride 、 溶剂黄146 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 8.0h， 生成 2-(2-Furyl)imidazo<4,5-b>phenazin
  参考文献：
  名称：

  A reversible fluorescent chemosensor for mercury ions based on 1H-imidazo[4,5-b]phenazine derivatives

  摘要：

  A series of non-sulfur, fluorescent sensors (S-6, S6-1 or S6-2) for mercury ions bearing 1H-imidazo[4,5-b]phenazine derivatives have been designed and synthesized. Among these sensors, a furan group into the sensor S-6 molecule was as the functional group, compound S6-1 containing the 5-(4-Nitrophenyl)-2-furan group was synthesized, and in order to establish the furan group's contribution to the sensor's fluorescent sensing abilities, compound S6-2, which without containing the furan group was also synthesized. S-6 showed excellent fluorescent specific selectivity and high sensitivity for Hg2+ in aqueous solution. The detection limit of the sensor towards Hg2+ is 1.6x10(-7) M, and other ions, including Fe3+, Ca2+, Cu2+, Co2+, Ni2+, Cd2+, Pb2+, Zn2+, Cr3+, and Mg2+ had nearly no influence on the probing behavior. Notably, this sensor serves as a recyclable component in sensing materials. The test strips based on S-6 were fabricated, which could act as a convenient and efficient Hg2+ test kits. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2013.07.007