Novel peptides which can act to inhibit renin and can have utility in the diagnosis and control of renin-dependent hypertension, and intermediates in the preparation of both the new and known renin-inhibiting peptides.
可抑制肾素并可用于诊断和控制肾素依赖性高血压的新型肽,以及制备新型和已知肾素抑制肽的中间体。
Renin-inhibiting peptides
申请人:THE UPJOHN COMPANY
公开号:EP0486478A2
公开(公告)日:1992-05-20
A renin inhibitory peptide comprising a N-alkylhistidine moiety at the position corresponding to the 9-position of the human renin substrate.