benthaphenone | 1275540-49-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: benthaphenone
• 英文别名: (2-Hydroxy-4,6-dimethoxyphenyl)-(7-hydroxy-2,2-dimethylchromen-5-yl)methanone；(2-hydroxy-4,6-dimethoxyphenyl)-(7-hydroxy-2,2-dimethylchromen-5-yl)methanone
• CAS: 1275540-49-2
• 化学式: C₂₀H₂₀O₆
• 分子量: 356.375
• InChiKey: BARZGEQZVUHGGI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  26
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  85.2
• 氢给体数：
  2
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  重氮甲烷 、 benthaphenone 以 乙醚 为溶剂， 生成 2,5'-di-O-methylbenthaphenone
  参考文献：
  名称：

  Friedolanostane, friedocycloartane and benzophenone constituents of the bark and leaves of Garcinia benthami

  摘要：

  Friedolanostanes, (22Z,24E)-3 beta-acetoxy-9 alpha-hydroxy-17,14-friedolanosta-14,22,24-trien-26-oic acid, (22Z,24E)-3 beta,9 alpha-dihydroxy-17,14-friedolanosta-14,22,24-trien-26-oic acid, (22Z,24E)-9 alpha-hydroxy-3-oxo-17,14-friedolanosta-14,22,24-trien-26-oic acid, a friedocycloartane, (22Z,24E)-3 alpha-hydroxy-17,13-friedocycloarta-12,22,24-trien-26-oic acid, and a benzophenone, benthaphenone, together with known compounds (22Z,24E)-3 alpha,9 alpha-dihydroxy-17,13-friedolanosta-12,22,24-trien-26-oic acid, methyl (24E)-3 alpha,23-dihydroxy-17,14-friedolanosta-8,14,24-trien-26-oate, glutinol, lupeol, and stigmasterol, were isolated from leaves and bark of Garcinia benthami. Their structures were elucidated using spectroscopic techniques, mainly 1-D and 2-D NMR spectroscopy, and chemical correlations. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.phytochem.2010.11.016

文献信息

• Friedolanostane, friedocycloartane and benzophenone constituents of the bark and leaves of Garcinia benthami
  作者：Hiep D. Nguyen、Binh T.D. Trinh、Quyen N. Tran、Hoan D. Nguyen、Hung D. Pham、Poul Erik Hansen、Fritz Duus、Joseph D. Connolly、Lien-Hoa D. Nguyen

  DOI：10.1016/j.phytochem.2010.11.016

  日期：2011.2

  Friedolanostanes, (22Z,24E)-3 beta-acetoxy-9 alpha-hydroxy-17,14-friedolanosta-14,22,24-trien-26-oic acid, (22Z,24E)-3 beta,9 alpha-dihydroxy-17,14-friedolanosta-14,22,24-trien-26-oic acid, (22Z,24E)-9 alpha-hydroxy-3-oxo-17,14-friedolanosta-14,22,24-trien-26-oic acid, a friedocycloartane, (22Z,24E)-3 alpha-hydroxy-17,13-friedocycloarta-12,22,24-trien-26-oic acid, and a benzophenone, benthaphenone, together with known compounds (22Z,24E)-3 alpha,9 alpha-dihydroxy-17,13-friedolanosta-12,22,24-trien-26-oic acid, methyl (24E)-3 alpha,23-dihydroxy-17,14-friedolanosta-8,14,24-trien-26-oate, glutinol, lupeol, and stigmasterol, were isolated from leaves and bark of Garcinia benthami. Their structures were elucidated using spectroscopic techniques, mainly 1-D and 2-D NMR spectroscopy, and chemical correlations. (C) 2010 Elsevier Ltd. All rights reserved.