5,10,15,20-tetraphenylporphyrin

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 四吡咯及其衍生物
• 英文名称: 5,10,15,20-tetraphenylporphyrin
• 化学式: C₄₄H₂₈N₄
• 分子量: 612.7
• InChiKey: ASQZPNGAQXZRMQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.6
• 重原子数：
  48
• 可旋转键数：
  4
• 环数：
  9.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  49.4
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• [EN] NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES<br/>[FR] NOUVEAUX COMPOSÉS HÉTÉROARYLE-TRIAZOLE EN TANT QUE PESTICIDES
  申请人：BAYER AG

  公开号：WO2021105091A1

  公开（公告）日：2021-06-03

  The present invention relates to novel heteroaryl-triazole compounds of the general formula (I), in which the structural elements X, R1, R2, R3, R4 and R5 have the meaning given in the description, to formulations and compositions comprising such compounds and for their use in the control of animal pests including arthropods and insects in plant protection and to their use for control of ectoparasites on animals.

  本发明涉及一种新颖的杂环芳基-三唑化合物，其一般式为（I），其中结构元素X、R1、R2、R3、R4和R5的含义如描述中所述，以及包含这些化合物的配方和组合物，用于控制包括节肢动物和昆虫在内的动物害虫，用于植物保护，并用于控制动物体表寄生虫。
• CARBORANYLPORPHYRINS AND USES THEREOF
  申请人：Wu Haitao

  公开号：US20050287073A1

  公开（公告）日：2005-12-29

  The present invention is directed to low toxicity boronated compounds and methods for their use in the treatment, visualization, and diagnosis of tumors. More specifically, the present invention is directed to low toxicity carborane-containing 5,10,15,20-tetraphenylporphyrin compounds and methods for their use particularly in boron neutron capture therapy (BNCT) and photodynamic therapy (PDT) for the treatment of tumors of the brain, head, neck, and surrounding tissue. The invention is also directed to using these carborane-containing tetraphenyl porphyrin compounds to methods of tumor imaging and/or diagnosis such as MRI, SPECT, or PET.

  本发明涉及低毒性硼化合物及其在肿瘤治疗、可视化和诊断中的应用方法。更具体地说，本发明涉及低毒性的含有碳硼烷的5,10,15,20-四苯基卟啉化合物，以及它们在脑部、头部、颈部和周围组织肿瘤治疗中的应用方法，特别是硼中子俘获疗法（BNCT）和光动力疗法（PDT）。该发明还涉及使用这些含有碳硼烷的四苯基卟啉化合物进行肿瘤成像和/或诊断的方法，例如MRI、SPECT或PET。
• Glycosylated Carboranylporphyrins and Uses Thereof
  申请人：Miura Michiko

  公开号：US20080279781A1

  公开（公告）日：2008-11-13

  The present invention is directed to low toxicity boronated compounds and methods for their use in the treatment, visualization, and diagnosis of tumors. More specifically, the present invention is directed to low toxicity glycosylated carborane-containing 5,10,15,20-tetraphenylporphyrin compounds and methods for their use particularly in boron neutron capture therapy (BNCT) and photodynamic therapy (PDT) for the treatment of tumors of the brain, and head and neck. The invention is also directed to using these glycosylated carborane-containing tetraphenylporphyrin compounds in methods of tumor imaging and/or diagnosis such as MRI, SPECT, or PET.

  本发明涉及低毒性硼化合物及其在肿瘤治疗、可视化和诊断中的使用方法。更具体地说，本发明涉及低毒性糖基化的含有5,10,15,20-四苯基卟啉的碳硼烷化合物及其在硼中子俘获治疗（BNCT）和光动力疗法（PDT）中的使用方法，特别用于治疗脑部、头颈部肿瘤。该发明还涉及使用这些糖基化的碳硼烷化合物在肿瘤成像和/或诊断方法中的应用，如MRI、SPECT或PET。
• Symmetric and Asymmetric Halogen-Containing Metallocarboranylporphyrins and Uses Thereof
  申请人：Miura Michiko

  公开号：US20080233047A1

  公开（公告）日：2008-09-25

  The present invention is directed to low toxicity boronated compounds and methods for their use in the treatment, visualization, and diagnosis of tumors. More specifically, the present invention is directed to low toxicity halogenated, carborane-containing 5,10,15,20-tetraphenylporphyrin compounds and methods for their use particularly in boron neutron capture therapy (BNCT) and photodynamic therapy (PDT) for the treatment of tumors of the brain, head and neck, and surrounding tissue. The invention is also directed to using these halogenated, carborane-containing tetraphenylporphyrin compounds in methods of tumor imaging and/or diagnosis such as MRI, SPECT, or PET.

  本发明涉及低毒性硼化合物及其在肿瘤治疗、可视化和诊断中的应用方法。更具体地说，本发明涉及低毒性卤代、含碳硼烷的5,10,15,20-四苯基卟啉化合物及其在硼中子俘获治疗（BNCT）和光动力疗法（PDT）中的应用方法，特别用于治疗脑部、头颈部和周围组织的肿瘤。该发明还涉及将这些卤代、含碳硼烷的四苯基卟啉化合物用于肿瘤成像和/或诊断的方法，例如MRI、SPECT或PET。
• LANTHANIDE COMPLEXES COMPRISING DENDRIMERS
  申请人：UNIVERSITE D'ORLEANS

  公开号：US20190352511A1

  公开（公告）日：2019-11-21

  The present invention relates to a complex comprising at least one dendrimer and at least one lanthanide, wherein the dendrimer comprises a unit of formula (I) below: in which: C 1 is a valence group 4 of formula >N—CH 2 —CH 2 —N<; A 1 , A 2 and A 3 are groups of formula —(CH 2 ) 2 —C(O)—NH—(CH 2 ) 2 —; the unit of formula (I) being connected covalently to at least one antenna which absorbs at a wavelength ranging from 500 nm to 900 nm.

  本发明涉及一种至少包括一种树状聚合物和至少一种镧系元素的复合物，其中该树状聚合物包括下面的式(I)的一个单元：其中：C1是一个价态为4的基团，具有式>N—CH2— —N<；A1、A2和A3是具有式—( )2—C(O)—NH—( )2—的基团；式(I)的单元与至少一个在500纳米到900纳米范围内吸收的天线共价连接。