Benzoylnorpseudotropin | 123202-90-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Benzoylnorpseudotropin
• 英文别名: Benzoylnortropin；3β-Benzoyloxy-nortropan；Nortropacocain；3-benzoyloxy-nortropane；endo-benzoic acid 8-aza-bicyclo[3.2.1]oct-3-yl ester；8-Azabicyclo[3.2.1]octan-3-yl benzoate
• CAS: 123202-90-4
• 化学式: C₁₄H₁₇NO₂
• 分子量: 231.294
• InChiKey: AZHSHGVBEAPALY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  17
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  38.3
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• NOVEL COMPOUNDS
  申请人：Peters Dan

  公开号：US20120004257A1

  公开（公告）日：2012-01-05

  The present applications discloses novel 8-aza-bicyclo[3.2.1]oct-3-yloxy)chromen-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors. In other aspects the applications discloses the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.

  本申请公开了新颖的8-aza-bicyclo[3.2.1]oct-3-yloxy)chromen-2-one衍生物及其作为单胺神经递质再摄取抑制剂的用途。在其他方面，该申请还公开了这些化合物在治疗方法中的用途，以及包括本发明化合物的药物组合物。
• Novel chromen-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
  申请人：NeuroSearch AS

  公开号：EP2311835A1

  公开（公告）日：2011-04-20

  This invention relates to novel chromen-2-one derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.

  本发明涉及可用作单胺神经递质再摄取抑制剂的新型色烯-2-酮衍生物。 在其他方面，本发明涉及这些化合物在治疗方法中的用途以及包含本发明化合物的药物组合物。
• 8-AZA-BICYCLO[3.2.1]OCTANE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS
  申请人：NeuroSearch A/S

  公开号：EP1948653A1

  公开（公告）日：2008-07-30
• NOVEL CHROMEN-2-ONE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS
  申请人：NeuroSearch A/S

  公开号：EP1989202B1

  公开（公告）日：2012-07-25
• CHROMEN-2-ONE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS
  申请人：Aniona ApS

  公开号：EP2430020B1

  公开（公告）日：2013-10-09