5'-O-[双(4-甲氧基苯基)苯基甲基]-2'-O-(2-甲氧基乙基)-5-甲基尿苷 | 163759-50-0

物质功能分类

医药中间体

分子结构分类

有机化合物 - 苯类化合物 - 三苯基化合物

中文名称

5'-O-[双(4-甲氧基苯基)苯基甲基]-2'-O-(2-甲氧基乙基)-5-甲基尿苷

中文别名

5'-O-(双(4-甲氧基苯基)苯基甲基)-2'-O-(2-甲氧基乙基)-5-甲基尿苷

英文名称

5'-O-(4,4'-dimethoxytriphenylmethyl)-2'-O-(2-methoxyethyl)-5-methyluridine

英文别名

1-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-(2-methoxyethoxy)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione；2'-O-methoxyethyl-5'-O-dimethoxytrityl-5-methyluridine；1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-(2-methoxyethoxy)oxolan-2-yl]-5-methylpyrimidine-2,4-dione

5'-O-[双(4-甲氧基苯基)苯基甲基]-2'-O-(2-甲氧基乙基)-5-甲基尿苷化学式

CAS

163759-50-0

化学式

C₃₄H₃₈N₂O₉

mdl

——

分子量

618.684

InChiKey

WIPCVBQXKBWNRC-PBAMLIMUSA-N

BEILSTEIN

——

EINECS

——

物化性质

密度：

1.32

计算性质

辛醇/水分配系数(LogP)：

3.1
重原子数：

45
可旋转键数：

13
环数：

5.0
sp3杂化的碳原子比例：

0.35
拓扑面积：

125
氢给体数：

2
氢受体数：

9

上下游信息

上游原料

中文名称	英文名称	CAS号	化学式	分子量
——	MOE T DMT succinate	730979-83-6	C₃₈H₄₂N₂O₁₂	718.758
2’-O-(2-甲氧基乙基)-5-甲基尿苷	2'-O-(2-methoxyethyl)-5-methyluridine	163759-49-7	C₁₃H₂₀N₂O₇	316.311
——	3-Benzyloxymethyl-1-[(2R,3R,4R,5R)-4-(2,4-dichloro-benzyloxy)-5-(2,4-dichloro-benzyloxymethyl)-3-(2-methoxy-ethoxy)-tetrahydro-furan-2-yl]-5-methyl-1H-pyrimidine-2,4-dione	163759-46-4	C₃₅H₃₆Cl₄N₂O₈	754.491
——	3-<(Benzyloxy)methyl>-1-<3',5'-bis-O-(2,4-dichlorobenzyl)-β-D-ribofuranosyl>thymin	163759-45-3	C₃₂H₃₀Cl₄N₂O₇	696.411
5-甲基尿甙	5-Methyluridine	1463-10-1	C₁₀H₁₄N₂O₆	258.231
L-胸苷	5-methyluridine	26879-47-0	C₁₀H₁₄N₂O₆	258.231
——	2,2'-anhydro-1-[2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-β-D-arabinofuranosyl-5-methyluridine]	817623-11-3	C₃₁H₃₀N₂O₇	542.588
2,2'-O-脱水-5-甲基尿嘧啶核苷	O-2,2'-cyclo-5-methyluridine	22423-26-3	C₁₀H₁₂N₂O₅	240.216

下游产品

中文名称	英文名称	CAS号	化学式	分子量
——	MOE T DMT succinate	730979-83-6	C₃₈H₄₂N₂O₁₂	718.758
——	2'-O-methoxyethyl-5'-O-dimethoxytrityl-5-methylcytidine	182496-00-0	C₃₄H₃₉N₃O₈	617.699
5-甲基-DMT-2'-甲氧基尿苷	[5'-O-(4,4'-dimethoxytriphenylmethyl)-2'-O-(2-methoxyethyl)-5-methyluridin-3'-O-yl]-2-cyanoethyl-N,N-diisopropylphosphoramidite	163878-63-5	C₄₃H₅₅N₄O₁₀P	818.904
——	[(2R,3R,4R,5R)-2-(hydroxymethyl)-4-(2-methoxyethoxy)-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-3-yl] benzoate	1345562-35-7	C₂₀H₂₄N₂O₈	420.419
2’-O-(2-甲氧基乙基)-5-甲基尿苷	2'-O-(2-methoxyethyl)-5-methyluridine	163759-49-7	C₁₃H₂₀N₂O₇	316.311
——	5-methyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(2-methoxyethyl)-3'-O-(N,N-diisopropylamino)-[2-[N-isopropyl-N-(4-methoxybenzoyl)amino]ethoxy]phosphinyluridine	291299-94-0	C₅₃H₆₉N₄O₁₂P	985.124
N-苯甲酰基-2'-O-甲氧基乙基-5-O-二甲氧基三苯甲基-5-甲基胞苷	5'-O-(4,4'-dimethoxytriphenylmethyl)-2'-O-(2-methoxyethyl)-N4-benzoyl-5-methylcytidine	182496-01-1	C₄₁H₄₃N₃O₉	721.807
——	[(2R,3R,4R,5R)-2-(2-diethoxyphosphoryl-2-hydroxyethyl)-4-(2-methoxyethoxy)-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-3-yl] benzoate	1345720-29-7	C₂₅H₃₅N₂O₁₁P	570.533
——	[(2R,3R,4R,5R)-2-[(1S,2S)-2-diethoxyphosphoryl-1,2-dihydroxyethyl]-4-(2-methoxyethoxy)-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-3-yl] benzoate	1345720-07-1	C₂₅H₃₅N₂O₁₂P	586.533
——	[(2R,3R,4R,5R)-2-[(1R,2R)-2-diethoxyphosphoryl-1,2-dihydroxyethyl]-4-(2-methoxyethoxy)-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-3-yl] benzoate	1345720-10-6	C₂₅H₃₅N₂O₁₂P	586.533
——	MOE 5-Me-C Amidite	163759-94-2	C₅₀H₆₀N₅O₁₀P	922.028
——	[(2R,3R,4R,5R)-2-(2-azido-2-diethoxyphosphorylethyl)-4-(2-methoxyethoxy)-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-3-yl] benzoate	1345720-31-1	C₂₅H₃₄N₅O₁₀P	595.546
——	2'-O-(2-methoxy)ethyl-3'-O-(t-butyldiphenyl)silylthymidine	844504-17-2	C₂₉H₃₈N₂O₇Si	554.715
——	[(2R,3R,4R,5R)-2-(1-azido-2-diethoxyphosphorylethyl)-4-(2-methoxyethoxy)-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-3-yl] benzoate	1345720-35-5	C₂₅H₃₄N₅O₁₀P	595.546
——	(2S,3S,4R,5R)-3-[tert-butyl(diphenyl)silyl]oxy-4-(2-methoxyethoxy)-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolane-2-carbaldehyde	1345564-47-7	C₂₉H₃₆N₂O₇Si	552.7
——	(2S,3S,4R,5R)-3-[tert-butyl(diphenyl)silyl]oxy-4-(2-methoxyethoxy)-5-[5-methyl-2,4-dioxo-3-(phenylmethoxymethyl)pyrimidin-1-yl]oxolane-2-carbaldehyde	1345561-88-7	C₃₇H₄₄N₂O₈Si	672.85

反应信息

作为反应物：

描述：

5'-O-[双(4-�