5,10,15,20-Tetrapyridin-4-ylporphyrin

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 四吡咯及其衍生物
• 英文名称: 5,10,15,20-Tetrapyridin-4-ylporphyrin
• 化学式: C₄₀H₂₄N₈
• 分子量: 616.7
• InChiKey: BWSWKIKSPYAKAP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.3
• 重原子数：
  48
• 可旋转键数：
  4
• 环数：
  9.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  101
• 氢给体数：
  0
• 氢受体数：
  8

文献信息

• Metal-porphyrin-complex-embedded liposomes, production process thereof, and medicines making use of the same
  申请人：Yuasa Makoto

  公开号：US20050008687A1

  公开（公告）日：2005-01-13

  An metalloporphyrin-complex-embedded liposome, comprising a cationic metalloporphyrin complex and a lipid having liposome forming ability is disclosed. As metalloporphyrin-complex-embedded liposomes according to the present invention act on superoxide anion radicals (O 2 − ), and can surely lower their concentration, they can exhibit superb effects for the treatment of cancers and have excellent characteristics as antioxidants.

  一种金属卟啉复合物嵌入的脂质体，包括阳离子金属卟啉复合物和具有脂质体形成能力的脂质体。根据本发明的金属卟啉复合物嵌入的脂质体对超氧阴离子自由基（O2−）起作用，可以有效降低其浓度，对于癌症的治疗具有出色的效果，并具有优秀的抗氧化特性。
• Nanoparticles of cyclic tetrapyrrolic compounds as gene and drug delivery carriers
  申请人：——

  公开号：US20040076585A1

  公开（公告）日：2004-04-22

  The present invention relates to a method using nanoparticles of cyclic tetrapyrrolic compounds as gene and drug delivery agents. Pharmaceutical agents can be packed or condensed inside nanoparticles of cyclic tetrapyrrolic compounds and delivered to cells. In vitro experiments showed nanoparticles of cyclic tetrapyrrolic compounds can be effectively delivered into cells.

  本发明涉及一种利用环四吡咯烷化合物的纳米颗粒作为基因和药物传递剂的方法。药物可以被包装或浓缩在环四吡咯烷化合物的纳米颗粒内，并传递到细胞中。体外实验表明，环四吡咯烷化合物的纳米颗粒可以有效地传递到细胞内。
• Organometallic compounds for the treatment of cancer
  申请人：Université de Neuchâtel

  公开号：EP1950217A1

  公开（公告）日：2008-07-30

  The present invention relates to novel organometallic compounds for use as a medicine, in particular in photodynamic therapy against various diseases, such as cancer. The compounds comprise a central porphyrin or phtalocyanine backbone to which ligand linkers coordinated to at least one transition metal are attached. Eta-5 or eta-6 arenes further bind to the transition metal. According to a preferred embodiment, the compound is a tetranuclear Ruthenium (+II) complex.

  本发明涉及一种新颖的有机金属化合物，用作药物，特别是用于光动力疗法对抗各种疾病，如癌症。这些化合物包括一个中央的卟啉或酞菁骨架，配体连接物与至少一个过渡金属配位。Eta-5或eta-6芳烃进一步与过渡金属结合。根据一个优选实施例，该化合物是一个四核钌（+II）配合物。
• Method to prepare porphyrin nanoparticles and its application as oxidation catalyst
  申请人：——

  公开号：US20030232982A1

  公开（公告）日：2003-12-18

  The present invention relates to a method to prepare porphyrin nanoparticles and its application as oxidation catalyst. Mixing solvent techniques was used to prepare porphyrin nanoparticles. The sizes of the resulted porphyin nanoparticles are in the range of 1-1000 nm. The resulted porphyrin nanoparticles were characterized by DLS, AFM and UV-Vis. The nanoparticles are stable in air from weeks to months and has been successfully transferred to Al 2 O 3 and silica gel surface. The present invention also related to a method to use nanoparticles of porphyrins as catalyst for epoxidation reactions of olefins and hydroxylation reactions of saturated hydrocarbons. By loading the nanoparticles onto the surface of Al 2 O 3 and silica gel, excellent catalytic activities were obtained in oxidation reactions.

  本发明涉及一种制备卟啉纳米颗粒及其作为氧化催化剂的应用方法。采用混合溶剂技术制备卟啉纳米颗粒，所得到的卟啉纳米颗粒的尺寸在1-1000纳米范围内。所得到的卟啉纳米颗粒通过DLS、AFM和UV-Vis进行表征。这些纳米颗粒在空气中稳定，可以保持数周至数月，并成功地转移到Al2O3和二氧化硅凝胶表面。本发明还涉及一种使用卟啉纳米颗粒作为烯烃环氧化反应和饱和烃羟化反应催化剂的方法。通过将纳米颗粒载入Al2O3和二氧化硅凝胶表面，可以获得优异的氧化反应催化活性。
• COLOR MATERIAL DISPERSION LIQUID, COMPOSITION, FILM, OPTICAL FILTER AND DISPLAY DEVICE
  申请人：DAI NIPPON PRINTING CO., LTD.

  公开号：US20210189137A1

  公开（公告）日：2021-06-24

  A color material dispersion liquid including a color material, which is a salt-forming compound of an organic dye with a heteropolyoxometalate, a dispersant and a solvent, wherein the organic dye is at least one organic dye selected from the group consisting of a porphyrin dye, a tetraazaporphyrin dye, a phthalocyanine dye and a squarylium dye, and wherein the heteropolyoxometalate is a heteropolyoxometalate which has an oxidation-reduction potential larger than −0.3 V relative to the silver/silver chloride electrode.

  一种颜色材料分散液，包括颜色材料、分散剂和溶剂。其中，颜色材料是有机染料与杂多金属酸盐形成的盐化合物，所述有机染料至少是从卟啉染料、四氮杂卟啉染料、酞菁染料和方酰亚胺染料中选择的至少一种有机染料，所述杂多金属酸盐是具有相对于银/银氯化物电极大于-0.3 V的氧化还原电位的杂多金属酸盐。