Pentafluorophenyl-[1-p-tolyl-meth-(E)-ylidene]-amine

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Pentafluorophenyl-[1-p-tolyl-meth-(E)-ylidene]-amine
• 英文别名: 1-(4-methylphenyl)-N-(2,3,4,5,6-pentafluorophenyl)methanimine
• 化学式: C₁₄H₈F₅N
• 分子量: 285.216
• InChiKey: FCXJUDHNFCKEEF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  20
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  12.4
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  Pentafluorophenyl-[1-p-tolyl-meth-(E)-ylidene]-amine 在 盐酸 作用下， 以 苯 为溶剂， 反应 56.0h， 生成 (Pentafluorophenylamino-p-tolyl-methyl)-phosphonic acid
  参考文献：
  名称：

  新型α-(N-五氟-苯胺基)苄基膦酸酯和膦酸的合成

  摘要：

  摘要 通过将 N-五氟苯基芳香醛亚胺与亚磷酸二烷基酯加成合成的相应膦酸酯 C6F5NHCH(Ar)P(O)(OR)2 水解，制备了一系列新型 α-(N-五氟苯基氨基)苄基膦酸。 . 展示了 C6F5NHCH(4-CH3C6H4)P(O)(OCH3) 的 X 射线衍射。

  DOI：

  10.1080/10426509608046365

文献信息

• Synthesis of neutral nickel–methyl complexes with monodentate imines and their sequential insertion of carbon monoxide and imine
  作者：Carolyne Stafford、Bruce A. Arndtsen

  DOI：10.1016/j.ica.2010.12.024

  日期：2011.4

  Neutral nickel-imine complexes of the form (N boolean AND O)Ni(R)((RN)-N-1=C(H)R-2) (N boolean AND O = salicylaldiminato; R = CH3, Ph; R-1 = alkyl; R-2 = aryl) can be prepared by the reaction of (tmeda)Ni(CH3)(2), imine and the corresponding salicylaldiminato ligand. The addition of carbon monoxide to these complexes lead to the in situ generation of the corresponding nickel-acyl complexes. With N-methyl or N-benzyl substituted imines, these complexes reductively eliminate the phenolic and acyl ligands to generate esters. However, the less sterically encumbered 3,4-dihydroisoquinoline can couple with the nickel-acyl ligand to form 1,2-diamides in high yield. In situ H-1 NMR analysis suggests this reaction occurs via insertion of imine into the nickel-acyl bond to form a nickel-bound amide complex.[GRAPHICS](C) 2010 Elsevier B. V. All rights reserved.
• SYNTHESIS OF NOVEL α-(N-PENTAFLUORO-PHENYLAMINO)BENZYLPHOSPHONATES AND PHOSPHONIC ACIDS
  作者：Shizheng Zhu、Bin Xu、Jie Zhang、Chaoyue Qin、Qicheng Huang、Chunxu Qu

  DOI：10.1080/10426509608046365

  日期：1996.5.1

  Abstract A series of novel α-(N-pentafluorophenylamino)benzyl phosphonic acids are prepared by hydrolysis of corresponding phosphonates, C6F5NHCH(Ar)P(O)(OR)2 which are synthesized from the addition of N-pentafluorophenyl aromatic aldimines with dialkyl phosphite. The X-ray diffraction of C6F5NHCH(4-CH3C6H4)P(O)(OCH3), is presented.

  摘要 通过将 N-五氟苯基芳香醛亚胺与亚磷酸二烷基酯加成合成的相应膦酸酯 C6F5NHCH(Ar)P(O)(OR)2 水解，制备了一系列新型 α-(N-五氟苯基氨基)苄基膦酸。 . 展示了 C6F5NHCH(4-CH3C6H4)P(O)(OCH3) 的 X 射线衍射。