N'-(3-aminopropyl)-N'-[3-[2-[2-[3-[bis(3-aminopropyl)amino]propoxy]ethoxy]ethoxy]propyl]propane-1,3-diamine | 851805-39-5

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N'-(3-aminopropyl)-N'-[3-[2-[2-[3-[bis(3-aminopropyl)amino]propoxy]ethoxy]ethoxy]propyl]propane-1,3-diamine
• CAS: 851805-39-5
• 化学式: C₂₂H₅₂N₆O₃
• 分子量: 448.693
• InChiKey: VQSIJRFQLLPXFK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.8
• 重原子数：
  31
• 可旋转键数：
  26
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  138
• 氢给体数：
  4
• 氢受体数：
  9

反应信息

• 作为反应物：
  描述：

  N'-(3-aminopropyl)-N'-[3-[2-[2-[3-[bis(3-aminopropyl)amino]propoxy]ethoxy]ethoxy]propyl]propane-1,3-diamine 、 丙烯酸甲酯（MA） 以 水 为溶剂， 反应 81.0h， 以46%的产率得到methyl 3-[3-[3-[2-[2-[3-[bis[3-[bis(3-methoxy-3-oxopropyl)amino]propyl]amino]propoxy]ethoxy]ethoxy]propyl-[3-[bis(3-methoxy-3-oxopropyl)amino]propyl]amino]propyl-(3-methoxy-3-oxopropyl)amino]propanoate
  参考文献：
  名称：

  New polyfunctional dendritic linear hybrids from terminal amine polyether oligomers (Jeffamine®): synthesis and characterization

  摘要：

  New dendritic polyether oligomers were synthesized from three different Jeffamines((R)) and characterized. This class of polyfunctional oligomers, bearing on their surface methylester, carboxylic acid, nitrile or amine groups, could be interesting modifying agents to change the properties of materials. The optimization of the iterative synthetic methods, through Michael addition, hydrolysis or hydrogenation, gave first and second generation dendritic structures in good yields. (c) 2005 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2005.02.086
• 作为产物：
  描述：

  3-[3-[2-[2-[3-[Bis(2-cyanoethyl)amino]propoxy]ethoxy]ethoxy]propyl-(2-cyanoethyl)amino]propanenitrile 在 platinum(IV) oxide 盐酸 、 氢气 作用下， 以 乙醇 为溶剂， 25.0 ℃ 、310.26 kPa 条件下， 反应 17.0h， 以95%的产率得到N'-(3-aminopropyl)-N'-[3-[2-[2-[3-[bis(3-aminopropyl)amino]propoxy]ethoxy]ethoxy]propyl]propane-1,3-diamine
  参考文献：
  名称：

  New polyfunctional dendritic linear hybrids from terminal amine polyether oligomers (Jeffamine®): synthesis and characterization

  摘要：

  New dendritic polyether oligomers were synthesized from three different Jeffamines((R)) and characterized. This class of polyfunctional oligomers, bearing on their surface methylester, carboxylic acid, nitrile or amine groups, could be interesting modifying agents to change the properties of materials. The optimization of the iterative synthetic methods, through Michael addition, hydrolysis or hydrogenation, gave first and second generation dendritic structures in good yields. (c) 2005 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2005.02.086

文献信息

• New polyfunctional dendritic linear hybrids from terminal amine polyether oligomers (Jeffamine®): synthesis and characterization
  作者：Pablo Froimowicz、Alessandro Gandini、Miriam Strumia

  DOI：10.1016/j.tetlet.2005.02.086

  日期：2005.4

  New dendritic polyether oligomers were synthesized from three different Jeffamines((R)) and characterized. This class of polyfunctional oligomers, bearing on their surface methylester, carboxylic acid, nitrile or amine groups, could be interesting modifying agents to change the properties of materials. The optimization of the iterative synthetic methods, through Michael addition, hydrolysis or hydrogenation, gave first and second generation dendritic structures in good yields. (c) 2005 Elsevier Ltd. All rights reserved.