(3-Ethoxyphenyl)-(2,3,4-trihydroxyphenyl)methanone

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (3-Ethoxyphenyl)-(2,3,4-trihydroxyphenyl)methanone
• 化学式: C₁₅H₁₄O₅
• 分子量: 274.27
• InChiKey: GIPLQLQEWXCSIX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  20
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.13
• 拓扑面积：
  87
• 氢给体数：
  3
• 氢受体数：
  5

文献信息

• Methods for treating congenital disorders of glycosylation
  申请人：Maggie's Pearl, LLC

  公开号：US11160794B2

  公开（公告）日：2021-11-02

  The present disclosure relates generally to compounds and pharmaceutical compositions for increasing glycosylation and treating congenital disorders of glycosylation.

  本公开一般涉及用于增加糖基化和治疗先天性糖基化紊乱的化合物和药物组合物。
• COMPOUNDS AND METHODS FOR MODULATING PROTEIN TRAFFICKING
  申请人：Bulawa Christine

  公开号：US20100305068A1

  公开（公告）日：2010-12-02

  Disclosed are compositions and methods for modulating protein trafficking and treating or preventing disorders characterized by impaired protein trafficking. Also disclosed are methods for producing a protein and identifying compounds that rescue protein trafficking defects.
• METHODS FOR TREATING CONGENITAL DISORDERS OF GLYCOSYLATION
  申请人：Perlara PBC

  公开号：US20210030721A1

  公开（公告）日：2021-02-04

  The present disclosure relates generally to compounds and pharmaceutical compositions for increasing glycosylation and treating congenital disorders of glycosylation.
• [EN] BENZOPHENONE COMPOUNDS<br/>[FR] COMPOSÉS DE BENZOPHÉNONE
  申请人：UNIV SHEFFIELD

  公开号：WO2009081141A1

  公开（公告）日：2009-07-02

  The invention relates to a series of benzophenone compounds of formula (I): wherein R1 and R2 are as defined herein, to pharmaceutical compositions comprising said compounds and in particular, but not exclusively to the use of said compounds in the treatment of motor neurone disease or a disease where oxidative stress may be a contributory factor.
• [EN] METHODS FOR TREATING CONGENITAL DISORDERS OF GLYCOSYLATION<br/>[FR] MÉTHODES POUR TRAITER DES TROUBLES CONGÉNITAUX DE LA GLYCOSYLATION
  申请人：PERLARA PBC

  公开号：WO2020040831A1

  公开（公告）日：2020-02-27

  The present disclosure relates generally to compounds and pharmaceutical compositions for increasing glycosylation and treating congenital disorders of glycosylation.