HC6H3(OH)CHN(4-(CF3)C6H4) | 25165-80-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: HC6H3(OH)CHN(4-(CF3)C6H4)
• 英文别名: N-salicylidene-4-trifluoromethylaniline；2-((E)-{[4-(trifluoromethyl)phenyl]imino}methyl)phenol；2-[[4-(trifluoromethyl)phenyl]iminomethyl]phenol
• CAS: 25165-80-4
• 化学式: C₁₄H₁₀F₃NO
• 分子量: 265.235
• InChiKey: GTJJEUWREOQQJC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  19
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  32.6
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  HC6H3(OH)CHN(4-(CF3)C6H4) 以 甲醇 、 苯 为溶剂， 生成
  参考文献：
  名称：

  Csaszar, Jozsef, Acta Chimica Hungarica, 1990, vol. 127, # 2, p. 166 - 169

  摘要：

  DOI：
• 作为产物：
  描述：

  以 甲醇 、 苯 为溶剂， 生成 HC6H3(OH)CHN(4-(CF3)C6H4)
  参考文献：
  名称：

  Csaszar, Jozsef, Acta Chimica Hungarica, 1990, vol. 127, # 2, p. 166 - 169

  摘要：

  DOI：

文献信息

• Trinuclear ruthenium carbonyl complexes with salicylaldimine ligands as efficient catalysts for the oxidation of secondary alcohols
  作者：Zhiqiang Hao、Ying Li、Zhihong Ma、Zhangang Han、Jin Lin、Guo-Liang Lu

  DOI：10.1016/j.jorganchem.2020.121647

  日期：2021.1

  A series of novel trinuclear ruthenium carbonyl complexes [µ-ƞ2-2-OC6H4-CH=N-Ar)]2Ru3(CO)8 [Ar = Ph (8), C6H4-4-Me (9), C6H4-4-CF3 (10), C6H4-4-Cl (11), C6H3-2,6-Me2 (12), C6H3-2,6-Et2 (13)] and [µ-ƞ2-2-OC6H4-CH=N-C6H3-2,6-iPr2]Ru3(CO)9 (14) were designed and synthesized. All the seven novel complexes were fully characterized by elemental analysis, IR and NMR spectroscopy. Molecular structures of 8

  一系列的新颖三核钌羰基配合物[ μ - ƞ 2 -2-OC 6 H ^ 4 -CH = N-AR）] 2的Ru 3（CO）8 [Ar为Ph（上8），C 6 H ^ 4 -4-箱（9），C 6 H ^ 4 -4-CF 3（10），C 6 H ^ 4 -4-CL（11），C 6 H ^ 3 -2,6-ME 2（12），C 6 H ^ 3 - 2,6-Et 2（13）]和[ μ - ƞ 2 -2-OC 6 H ^ 4 -CH = NC 6 H ^ 3 -2,6-我镨2 ]的Ru 3（CO）9（14），设计并合成。通过元素分析，IR和NMR光谱对7种新型配合物进行了全面表征。通过单晶X射线衍射进一步证实了8、11、13和14的分子结构。研究了这些配合物在仲醇氧化中的催化性能，发现这些配合物与N-甲基吗啉-N-氧化物（NMO）对仲醇的氧化显示出高催化活性，从而以优异的收率得到相应的羰基化合物。
• Synthesis of cyclic polylactide catalysed by bis(salicylaldiminato)tin(ii) complexes
  作者：Parichat Piromjitpong、Passachon Ratanapanee、Wipavee Thumrongpatanaraks、Palangpon Kongsaeree、Khamphee Phomphrai

  DOI：10.1039/c2dt31678a

  日期：——

  Eight bis(salicylaldiminato)tin(II) complexes have been synthesized from the reaction of Sn[N(SiMe3)2]2 and 2 equiv of the corresponding ligands at room temperature. The ligands, synthesized from salicylaldehyde and amines, were designed to have different electronic and steric properties using different amines to synthesize the tin(II) complexes as aniline (2a), 2,6-dimethylaniline (2b), 2,6-diisopropylaniline (2c), 4-methoxyaniline (2d), 4-trifluoromethylaniline (2e), methylamine (2g), and tert-butylamine (2h). Ligand variation at the salicyl group synthesized from 4-bromosalicylaldehyde and 2,6-diisopropylaniline was used to form complex 2f. Complex 2c was characterized crystallographically. All catalysts were active for the neat polymerization of L-lactide at 115 °C. At a lactide : Sn molar ratio of 10 : 1, cyclic polylactide (PLA) was obtained as demonstrated by 1H NMR and mass spectrometry. Addition of 1 equiv of benzyl alcohol in the polymerization produced linear PLA. At a higher lactide : Sn molar ratio of 200 : 1, high molecular weight PLAs with Mn up to 132 200 Daltons were obtained. Results from GPC coupled with light scattering detector and viscometer suggested that they are cyclic PLA. The order of reactivity based on conversion was determined to be 2c < 2b < 2a in accordance with lower steric hindrance. For electronic contribution, the order of 2e < 2a < 2d was observed in agreement with the increasing electron donation of the ligands. Complex 2g having the smallest substituents was found to be the most active catalyst.

  八种双（水杨醛亚氨基）锡（II）配合物已通过室温下Sn[N(SiMe3)2]2与相应配体的2当量反应合成。这些配体由水杨醛和胺合成，设计使用了不同的胺，以赋予其不同的电子和立体性质，从而合成锡（II）配合物，如苯胺（2a）、2,6-二甲基苯胺（2b）、2,6-二异丙基苯胺（2c）、4-甲氧基苯胺（2d）、4-三氟甲基苯胺（2e）、甲胺（2g）和叔丁胺（2h）。通过4-溴水杨醛和2,6-二异丙基苯胺合成的配体在水杨醛基团的变异被用来形成配合物2f。配合物2c通过晶体学进行了表征。所有催化剂在115°C下均对L-乳酸的内聚聚合活性良好。在乳酸：锡摩尔比为10：1时，通过1H NMR和质谱法证实得到了环状聚乳酸（PLA）。在聚合反应中加入1当量的苄醇产生了线性PLA。在更高的乳酸：锡摩尔比200：1下，得到了分子量高达132,200道尔顿的高分子量PLA。GPC结合光散射检测器和粘度计的结果表明它们是环状PLA。根据转化率确定的反应活性顺序为2c < 2b < 2a，这与较低的立体阻碍相符。对于电子贡献，观察到的顺序为2e < 2a < 2d，这与配体电子捐赠增加一致。具有最小取代基的配合物2g被发现是活性最高的催化剂。
• Synthesis, Structural Characterization, and Ethylene Polymerization Behavior of the Vanadium(III) Complexes Bearing Salicylaldiminato Ligands
  作者：Ji-Qian Wu、Li Pan、Ning-Hai Hu、Yue-Sheng Li

  DOI：10.1021/om800097b

  日期：2008.8.1

  activities, and produced polymers with low molecular weight (Mw < 30 kg/mol) and broad molecular weight distributions at 70 °C. Complexes 3a−k were also effective catalyst precursors for ethylene polymerization. Even at 70 °C these complexes produced polyethylenes with unimodal distributions. These results indicated that the structural model of the salicylaldiminato vanadium(III) complexes greatly affected

  带有水杨基铝亚氨基配体（2a - k）的钒（III）络合物[RN═CH（ArO）] VCl 2（THF）2（Ar = C 6 H 4，R = Ph，2a ; p -CF 3 Ph，2b ; p -CH 3 Ph，2c ; 2,6-Me 2 Ph，2d ; 2,6- i Pr 2 Ph，2e ;环己基，2f ; Ar = C 6 H 3 t Bu（2），R = Ph，2g ; 2,6-我Pr 2Ph，2h ; Ar = C 6 H 2 t Bu 2（2,4），R = Ph，2i ; 2,6- i Pr 2 Ph，2j ; 在过量的三乙胺（TEA）存在下，用1.0当量的（RN═CH）ArOH在四氢呋喃（THF）中处理，由VCl 3（THF）3制备Ar = C 6 H 2 Br 2，R = Ph，2k） 。在过量TEA存在下，VCl 3（THF）3与2.0当量的（RN═CH）ArOH在THF中反
• Asymmetric Synthesis of cis-4-Aminobenzopyran Derivatives Catalyzed by N,N′-Dioxide-Sc(OTf)3 Complexes
  作者：Yulong Zhang、Shunxi Dong、Xiaohua Liu、Mingsheng Xie、Yin Zhu、Lili Lin、Xiaoming Feng

  DOI：10.1002/chem.201102058

  日期：2011.12.2

  The reactions of salicylaldimines with electron‐rich alkenes (2,3‐dihydro‐2H‐furan and 3,4‐dihydro‐2H‐pyran) catalyzed by N,N′‐dioxide–Sc(OTf)3 complexes were investigated. The methodology was successfully applied to the asymmetric synthesis of cis‐4‐aminobenzopyran derivatives. Excellent yields, diastereo‐ and enantioselectivities were observed for a broad range of substrates under mild conditions

  研究了水杨醛亚胺与富含电子的烯烃（2,3-二氢-2 H-呋喃和3,4-二氢-2 H-吡喃）在N，N'-二氧化物-Sc（OTf）3配合物催化下的反应。该方法已成功地用于不对称合成顺-4-氨基苯并吡喃衍生物。在温和条件下，对多种底物均观察到优异的收率，非对映和对映选择性（参见方案）。
• Asymmetric Synthesis of 3,4-Diaminochroman-2-ones Promoted by Guanidine and Bisguanidium Salt
  作者：Shunxi Dong、Xiaohua Liu、Yulong Zhang、Lili Lin、Xiaoming Feng

  DOI：10.1021/ol2018888

  日期：2011.10.7

  A highly enantioselective synthesis of 3,4-diaminochroman-2-ones has been realized via the domino reaction of o-hydroxy aromatic aldimines and azlactones. Notably, a cis-product was obtained as the major product by the use of guanidine 2a whereas a trans-product was the major product with bisguanidium salt 3•HBArF4. In two cases, various substituted 3,4-dihydrocoumarins were obtained with high yields

  通过邻羟基芳族醛亚胺和a内酯的多米诺反应，已经实现了对3,4-二氨基苯并二氢吡喃-2-酮的高度对映选择性的合成。值得注意的是，通过使用胍2a获得了顺式产物作为主要产物，而反式产物是双胍盐3•HBAr F 4的主要产物。在两种情况下，以高收率（高达99％），出色的对映选择性（高达99％ee）和非对映选择性（高达> 99：1顺式：反式和98：2 ）获得了各种取代的3,4-二氢香豆素。反式：顺式，分别）在温和的反应条件下。