2-Methyl-1,4-dioxacyclotetradecane-5,14-dione

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 大环内酯类和类似物
• 英文名称: 2-Methyl-1,4-dioxacyclotetradecane-5,14-dione
• 化学式: C₁₃H₂₂O₄
• 分子量: 242.31
• InChiKey: JOZILNCSRASEMU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  17
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.85
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• Antifouling coating
  申请人：Nippon Paint Co., Ltd.

  公开号：EP1138725B1

  公开（公告）日：2007-09-12
• INTRALUMINAL POLYMERIC DEVICES FOR THE TREATMENT OF ANEURYSMS
  申请人：Yissum Research Development Company of The Hebrew University of Jerusalem

  公开号：EP2453940A2

  公开（公告）日：2012-05-23
• RENEWABLY DERIVED THERMOPLASTIC POLYESTER-BASED URETHANES AND METHODS OF MAKING AND USING THE SAME
  申请人：Trent University

  公开号：US20170145145A1

  公开（公告）日：2017-05-25

  The disclosure generally provides high-molecular-weight thermoplastic polyester-based urethanes (TPEUs). In some embodiments, the component monomers of the TPEUs are entirely derived from renewable sources. The disclosure also provides methods of making high-molecular-weight TPEUs, and, in particular, methods for achieving such high molecular weights. The disclosure also provides certain uses of such TPEUs. Entirely lipid-derived segmented thermoplastic TPEU elastomers with rubber-like properties such as low modulus and high elongation were produced by incorporating 1,9-nonanediol (ND) as chain extender with oleic acid derived polyester diols (PEDs) and 1,7-heptamethylene diisocyanate (HPMDI). Enhanced elastomeric properties were achieved by optimizing hydrogen bond density and phase separation of the TPEU via customized polymerization protocols. The novel TPEUs showed extensive degradation under hydrothermal ageing in water at 80° C. and achieved a tensile half-life in one day of immersion. For the first time, entirely lipid-derived TPEU elastomers with thermal and mechanical properties comparable to commercially available petroleum-based analogues and a controlled life-cycle were achieved, demonstrating the viability of potential alternatives to petroleum-derived elastomers and credible potential in biomedical applications especially as bio-resorbable implants or tissue scaffolds.
• READY-MADE BIOMEDICAL DEVICES FOR IN VIVO WELDING
  申请人：YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD

  公开号：US20170333604A1

  公开（公告）日：2017-11-23

  Disclosed herein is a unique family of medical implants which are engineered outside of a subject's body into a form which may be manipulated in vivo. The implants comprise a region of at least one weldable material which allows welding of the implant to a polymeric material introduced into the body prior to, together with or after the implant has been positioned.
• US3945955A
  申请人：——

  公开号：US3945955A

  公开（公告）日：1976-03-23