cannabicyclolic acid | 40524-99-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: cannabicyclolic acid
• 英文别名: CBLA；Cannabicycloic acid；1H-4-Oxabenzo[f]cyclobut[cd]indene-7-carboxylic acid, 1a,2,3,3a,8b,8c-hexahydro-8-hydroxy-1,1,3a-trimethyl-6-pentyl-; 1a,2,3,3a,8b,8c-Hexahydro-8-hydroxy-1,1,3a-trimethyl-6-pentyl-1H-4-oxabenzo[f]cyclobut[cd]indene-7-carboxylic acid; Cannabicyclolic acid; CBLA；3-hydroxy-9,13,13-trimethyl-5-pentyl-8-oxatetracyclo[7.4.1.02,7.012,14]tetradeca-2(7),3,5-triene-4-carboxylic acid
• CAS: 40524-99-0
• 化学式: C₂₂H₃₀O₄
• 分子量: 358.478
• InChiKey: JVOHLEIRDMVLHS-UHFFFAOYSA-N

物化性质

• 沸点：
  429.1±45.0 °C(Predicted)
• 密度：
  1.168±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  6.1
• 重原子数：
  26
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.68
• 拓扑面积：
  66.8
• 氢给体数：
  2
• 氢受体数：
  4

安全信息

• WGK Germany：
  2

文献信息

• Pharmaceutical composition and method of manufacturing
  申请人：Speier Gary J.

  公开号：US10238705B2

  公开（公告）日：2019-03-26

  The present invention provides for methods of obtaining an extract of Cannabis plant material as well as subsequent processing of the extract to provide a concentrate of Cannabis. The present invention also provides for pharmaceutical dosage forms (e.g., oral thin films and transdermal patches) that include the concentrate (or extract) of Cannabis, as well as methods of medical treatment that include administering the pharmaceutical dosage forms.

  本发明提供了获得大麻植物材料提取物的方法，以及对提取物进行后续加工以提 供大麻浓缩物的方法。本发明还提供了包括大麻浓缩物（或提取物）的药物剂型（如口服薄膜和透皮贴剂），以及包括施用药物剂型的医疗方法。
• PHARMACEUTICAL COMPOSITION AND METHOD OF MANUFACTURING
  申请人：Speier Gary J.

  公开号：US20150297653A1

  公开（公告）日：2015-10-22

  The present invention provides for methods of obtaining an extract of Cannabis plant material as well as subsequent processing of the extract to provide a concentrate of Cannabis . The present invention also provides for pharmaceutical dosage forms (e.g., oral thin films and transdermal patches) that include the concentrate (or extract) of Cannabis , as well as methods of medical treatment that include administering the pharmaceutical dosage forms.
• US9044390B1
  申请人：——

  公开号：US9044390B1

  公开（公告）日：2015-06-02
• US9186386B2
  申请人：——

  公开号：US9186386B2

  公开（公告）日：2015-11-17
• US9980996B2
  申请人：——

  公开号：US9980996B2

  公开（公告）日：2018-05-29