5,7-dimethyl-6,7-dihydro-5H-cyclopenta[b]pyridine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 5,7-dimethyl-6,7-dihydro-5H-cyclopenta[b]pyridine
• 化学式: C₁₀H₁₃N
• 分子量: 147.22
• InChiKey: MAHYVJAEGUGRHA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  11
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  12.9
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• Thiazole Carboxamide Derivatives and Their Use to Treat Cancer
  申请人：Shipps, JR. Gerald W.

  公开号：US20110044940A1

  公开（公告）日：2011-02-24

  The present invention relates to novel Heterocyclic Ether or Thioether Derivatives, compositions comprising the Heterocyclic Ether or Thioether Derivatives, and methods for using the Heterocyclic Ether or Thioether Derivatives for treating or preventing a proliferative disorder, an anti-proliferative disorder, inflammation, arthritis, a central nervous system disorder, a cardiovascular disease, alopecia, a neuronal disease, an ischemic injury, a viral infection, a fungal infection, or a disorder related to the activity of a protein kinase.

  本发明涉及新型杂环醚或硫醚衍生物，包括含有该杂环醚或硫醚衍生物的组合物，以及使用该杂环醚或硫醚衍生物治疗或预防增殖性疾病、抗增殖性疾病、炎症、关节炎、中枢神经系统疾病、心血管疾病、脱发、神经疾病、缺血性损伤、病毒感染、真菌感染或与蛋白激酶活性相关的疾病的方法。
• Novel Heterocyclic Compounds as Bromodomain Inhibitors
  申请人：Zenith Epigenetics Corp.

  公开号：US20160130228A1

  公开（公告）日：2016-05-12

  The present disclosure relates to compounds, which are useful for inhibition of BET protein function by binding to bromodomains, and their use in therapy.

  本公开涉及一些化合物，这些化合物通过结合溴域来抑制BET蛋白功能，并且这些化合物在治疗中的使用。
• 2-AMINOTHIAZOLE-4-CARBOXYLIC AMIDES AS PROTEIN KINASE INHIBITORS
  申请人：Shipps, JR. Gerald W.

  公开号：US20100055090A1

  公开（公告）日：2010-03-04

  The present invention relates to novel Anilinopiperazine Derivatives of formula (I), compositions comprising the Anilinopiperazine Derivatives, and methods for using the Anilinopiperazine Derivatives for treating or preventing a proliferative disorder, an anti-proliferative disorder, inflammation, arthritis, a central nervous system disorder, a cardiovascular disease, alopecia, a neuronal disease, an ischemic injury, a viral disease, a fungal infection, or a disorder related to the activity of a protein kinase.
• 4, 5-RING ANNULATED INDOLE DERIVATIVES FOR TREATING OR PREVENTING OF HCV AND RELATED VIRAL INFECTIONS
  申请人：Anilkumar Gopinadhan N.

  公开号：US20100196319A1

  公开（公告）日：2010-08-05

  The present invention relates to 4,5-ring annulated indole derivatives of formula (I), compositions comprising at least one 4,5-ring annulated indole derivatives, and methods of using the 4,5-ring annulated indole derivatives for treating or preventing a viral infection or a virus-related disorder in a patient, wherein ring Z of formula (I), is cyclohexyl, cyclohexenyl, 6-membered heterocycloalkyl, 6-membered heterocycloalkenyl, 6-membered aryl or 6-membered heteroaryl, wherein R 1 , R 2 , R 3 , R 6 , R 7 and R 10 are as described herein.
• Heterocyclic Urea and Thiourea Derivatives and Methods of Use Thereof
  申请人：Tadikonda Praveen K.

  公开号：US20110129440A1

  公开（公告）日：2011-06-02

  The present invention relates to novel Heterocyclic Urea and Thiourea Derivatives of formula (I), compositions comprising the Heterocyclic Urea and Thiourea Derivatives, and methods for using the Heterocyclic Urea and Thiourea Derivatives for treating or preventing a proliferative disorder, an anti-proliferative disorder, inflammation, arthritis, a central nervous system disorder, a cardiovascular disease, alopecia, a neuronal disease, an ischemic injury, a viral infection, a fungal infection, or a disorder related to the activity of a protein kinase.