2-[2-(2-Methoxyethoxy)ethoxy]ethyl-(3-methylbutyl)-phenylphosphane | 176445-50-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-[2-(2-Methoxyethoxy)ethoxy]ethyl-(3-methylbutyl)-phenylphosphane
• CAS: 176445-50-4
• 化学式: C₁₈H₃₁O₃P
• 分子量: 326.416
• InChiKey: NVNYQPLRYYAUKQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  22
• 可旋转键数：
  13
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  27.7
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  tris(triphenylphosphine)ruthenium(II) chloride 、 2-[2-(2-Methoxyethoxy)ethoxy]ethyl-(3-methylbutyl)-phenylphosphane 以 二氯甲烷 为溶剂， 以38%的产率得到
  参考文献：
  名称：

  新型半不稳定两亲性膦的合成。钌（II）的络合性质和催化氢加成反应

  摘要：

  新的功能化膦R-（C 6 H 4）（OCH 2 CH 2）n PPh 2 { 1（R =叔辛基，n = 1），2（R =叔辛基，n = 5），3（R =叔辛基，ñ = 13），4（R = ñ壬基，ñ = 1.4），5（R = ñ壬基，ñ = 5），6（R = ñ壬基，ñ = 11）}， CH3（OCH 2 CH 2）3 PPh 2（7），CH 3（OCH 2 CH 2）3 PPhR（8，R =异戊基）和HOCH 2 CH 2（OCH 2 CH 2）2 PPhR（9，R = n-辛基）已合成。这些配体在同一分子中包含聚醚和疏水基团，因此可以导致结合了半不稳定（聚醚基团）和两亲（疏水和亲水基团）特性的化合物。进行了Ru（II）的络合研究，并表征了异常的三齿（O，O，P）配位模式。在CO和[RuCl 2（8）（PPh 3）]反应后，从三齿（O，O，P）配位模式向双齿（O，P）和单齿（P）演化显示了半不稳定性。。双核[Ru

  DOI：

  10.1021/om9905916
• 作为产物：
  描述：

  二苯基膦酸锂 生成 2-[2-(2-Methoxyethoxy)ethoxy]ethyl-(3-methylbutyl)-phenylphosphane
  参考文献：
  名称：

  Study of the complexing properties toward Ru^IIof new polydentate amphiphilic phosphines containing polyether chains. Unprecedented η³mode of bonding of the new ligand PPh[(CH₂)₃CHMe₂][(CH₂CH₂O)₃Me] and study of its hemilabile character

  摘要：

  New polydentate amphiphilic phosphines containing polyether chains are prepared; unprecedented coordination and reactivity of the hemilabile ligand PPh[(CH2)(3)CHMe(2)][(CH2CH2O)(3)Me] are found; the eta(3) mode of bonding of this ligand is demonstrated by X-ray crystallographic studies.

  DOI：

  10.1039/cc9960000771

文献信息

• Palladium(II) complexes with hemilabile amphiphilic phosphines
  作者：Esteve Valls、Joan Suades、René Mathieu、Joan F Piniella、Angel Alvarez-Larena

  DOI：10.1016/s0022-328x(01)00663-5

  日期：2001.4

  A series of trans-PdCl2L2 complexes were prepared and characterized with the following hemilabile amphiphilic phosphines: R-(C6H4)-(OCH2CH2)(n)-PPh2 1 (R = tert-octyl, n = 1), 2 (R = tert-octyl, (n) over bar = 5), 3 (R = tert-octyl, (n) over bar = 13), 4 (R = n-nonyl, (n) over bar = 1.4), 5 (R = n-nonyl, (n) over bar = 5), 6 (R = n-nonyl, (n) over bar = 11)}, CH3(OCH2CH2)(3)PPh2 (7), CH3(OCH2CH2)(3)PPhR (8, R = isopentyl) and HOCH2CH2(OCH2CH2)(2)PPhR (9, R=n-octyl). The molecular structure of trans-PdCl2(1)(2) was determined by X-ray crystallography. The reaction between the trans-PdCl2L2 complexes and Ag+. was studied by P-31-NMR spectroscopy. The formation of chelated P boolean ANDO species in tetrahydrofuran solution was observed in complexes with ligands 2, 3, 5, 6, 7, 8 and 9. However, with ligand 1 the formation of chelated species was only observed in the less coordinating solvent dichloromethane. This different behavior can be attributed to the electronic and steric effects of the aryl group bonded to the oxygen atom. Ligand 4 is a mixture of a molecule similar to 1 and molecules with more than one oxygen atom and thus displays both characteristics. (C) 2001 Elsevier Science B.V. All rights reserved.
• Process for the partial hydrogenation of fatty acid esters
  申请人：Papadogianakis Georgios

  公开号：US20100022664A1

  公开（公告）日：2010-01-28

  Suggested is a process for the manufacture of unsaturated fatty acid alkyl esters or glycerides having a total content of C 18:1 of about 30 to about 80 Mol-% by partial hydrogenation of unsaturated fatty acid esters having a total content of (C18:2+C18:3) of at least 65 Mol-%—calculated on the total amount of C18 moieties in the ester—which is characterised in that the hydrogenation is conducted in an aqueous/organic two phase system in the presence of a water soluble catalyst consisting of a Group VIII metal and a hydrophilic ligand.
• US8263794B2
  申请人：——

  公开号：US8263794B2

  公开（公告）日：2012-09-11
• Study of the complexing properties toward Ru^IIof new polydentate amphiphilic phosphines containing polyether chains. Unprecedented η³mode of bonding of the new ligand PPh[(CH₂)₃CHMe₂][(CH₂CH₂O)₃Me] and study of its hemilabile character
  作者：Esteve Valls、Joan Suades、Bruno Donadieu、René Mathieu

  DOI：10.1039/cc9960000771

  日期：——

  New polydentate amphiphilic phosphines containing polyether chains are prepared; unprecedented coordination and reactivity of the hemilabile ligand PPh[(CH2)(3)CHMe(2)][(CH2CH2O)(3)Me] are found; the eta(3) mode of bonding of this ligand is demonstrated by X-ray crystallographic studies.
• Synthesis of New Hemilabile Amphiphilic Phosphines. Complexing Properties toward Ruthenium(II) and Catalytic Activity for Hydrogenation of Prenal
  作者：Esteve Valls、Joan Suades、René Mathieu

  DOI：10.1021/om9905916

  日期：1999.12.1

  from ligands with a short polyether chain (1, 4). The catalytic selective hydrogenation of an α,β-unsaturated aldehyde (prenal) with ruthenium complexes prepared in situ from RuCl3 and ligands 1−6 has been carried out in a 2-propanol/water mixture. Conversions to prenol to the order of 90% or higher are observed with selectivity of 90−96% after 20 min at P = 30 bar and T = 50 °C. The most active systems

  新的功能化膦R-（C 6 H 4）（OCH 2 CH 2）n PPh 2 1（R =叔辛基，n = 1），2（R =叔辛基，n = 5），3（R =叔辛基，ñ = 13），4（R = ñ壬基，ñ = 1.4），5（R = ñ壬基，ñ = 5），6（R = ñ壬基，ñ = 11）}， CH3（OCH 2 CH 2）3 PPh 2（7），CH 3（OCH 2 CH 2）3 PPhR（8，R =异戊基）和HOCH 2 CH 2（OCH 2 CH 2）2 PPhR（9，R = n-辛基）已合成。这些配体在同一分子中包含聚醚和疏水基团，因此可以导致结合了半不稳定（聚醚基团）和两亲（疏水和亲水基团）特性的化合物。进行了Ru（II）的络合研究，并表征了异常的三齿（O，O，P）配位模式。在CO和[RuCl 2（8）（PPh 3）]反应后，从三齿（O，O，P）配位模式向双齿（O，P）和单齿（P）演化显示了半不稳定性。。双核[Ru