1,3,6,8-Tetrahydroxy-2-(6-hydroxy-6-methyloxan-3-yl)anthracene-9,10-dione

• 分子结构分类: 有机化合物 - 苯类化合物 - 蒽
• 英文名称: 1,3,6,8-Tetrahydroxy-2-(6-hydroxy-6-methyloxan-3-yl)anthracene-9,10-dione
• 英文别名: 1,3,6,8-tetrahydroxy-2-(6-hydroxy-6-methyloxan-3-yl)anthracene-9,10-dione
• 化学式: C₂₀H₁₈O₈
• 分子量: 386.4
• InChiKey: MKIQOKFAFBXAKE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  28
• 可旋转键数：
  1
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  145
• 氢给体数：
  5
• 氢受体数：
  8

文献信息

• NATURAL PRODUCT ANTIBIOTICS AND ANALOGS THEREOF
  申请人：CHILDREN'S MEDICAL CENTER CORPORATION

  公开号：US20130245130A1

  公开（公告）日：2013-09-19

  Provided herein are pure and isolated natural products and analogs thereof of Formula (I), (II), (III), and (IV), pharmaceutical compositions thereof, and methods of use, for example, for treating a bacterial infection. Further provided are methods useful in identifying an inhibitor of bacterial sugar fermentation in a bacterial strain, such as a compound (inhibitor) of Formula (I), (II), (III), or (IV): or a pharmaceutically acceptable salt thereof.
• US9359275B2
  申请人：——

  公开号：US9359275B2

  公开（公告）日：2016-06-07