4-benzoyloxy-1,2,2,6,6-pentamethyl-piperidine-4-carboxylic acid methyl ester | 470-68-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-benzoyloxy-1,2,2,6,6-pentamethyl-piperidine-4-carboxylic acid methyl ester
• 英文别名: 4-Benzoyloxy-1,2,2,6,6-pentamethyl-piperidin-4-carbonsaeure-methylester；alpha-Eucaine；methyl 4-benzoyloxy-1,2,2,6,6-pentamethylpiperidine-4-carboxylate
• CAS: 470-68-8
• 化学式: C₁₉H₂₇NO₄
• 分子量: 333.428
• InChiKey: MJMZACWQGQGLBI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  24
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.58
• 拓扑面积：
  55.8
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  碘甲烷 、 alkaline earth salt of/the/ methylsulfuric acid 在 氢氧化钾 作用下， 生成 4-benzoyloxy-1,2,2,6,6-pentamethyl-piperidine-4-carboxylic acid methyl ester
  参考文献：
  名称：

  Merling, Berichte der Deutschen Pharmazeutischen Gesellschaft, vol. 6, p. 175

  摘要：

  DOI：

文献信息

• DE90245
  申请人：——

  公开号：——

  公开（公告）日：——
• Dispersible pharmaceutical composition for treatment of mastitis and otic disorders
  申请人：Britten Jean Nancy

  公开号：US20050009931A1

  公开（公告）日：2005-01-13

  A method is provided for treatment and/or prevention of an infective condition in a fluid-containing organ having a natural exterior orifice, such as the udder of a milk-producing animal or an ear of a subject. The invention also relates to a dispersible pharmaceutical composition suitable for infusion into the organ according to the method of the invention, and to a process for preparing such a composition.
• COMPOSITIONS AND METHODS FOR PREVENTING OR TREATING MUSCLE CONDITIONS
  申请人：The Board of Trustees of the Leland Stanford Junior University

  公开号：US20190167695A1

  公开（公告）日：2019-06-06

  Provided herein are compositions for preventing or treating muscle conditions such as muscle damage, injury, or atrophy. In some embodiments, the compositions comprise a prostaglandin E2 (PGE2) compound and a myotoxin. In some embodiments, the muscle damage, injury, or atrophy is the result of a nerve injury, a surgical procedure, or a traumatic injury. Methods of promoting muscle regeneration and methods of increasing muscle mass are also provided herein.
• Reducing or Inhibiting Ocular Damage by Hyaluronidase Administration
  申请人：Med Progress, LLC

  公开号：US20210361752A1

  公开（公告）日：2021-11-25

  The present disclosure discloses compositions comprising a hyaluronidase, devices comprising such compositions, as well as methods and uses employing such compositions and devices to reduce or eliminate a hyaluronic acid-induced blockage of one or more blood vessels supplying an eye of an individual; methods and uses for employing such compositions and devices to reduce or inhibit a vascular occlusion in an eye of an individual; and methods and uses for employing such compositions and devices to reduce or inhibit a hyaluronic acid-induced loss of vision of an individual.