羟基(苯基)乙酰基溴化物 | 133334-05-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 羟基(苯基)乙酰基溴化物
• 英文名称: Hydroxy(phenyl)acetyl bromide
• 英文别名: 2-hydroxy-2-phenylacetyl bromide
• CAS: 133334-05-1
• 化学式: C₈H₇BrO₂
• 分子量: 215.04
• InChiKey: NHJCKOWSTNHCIU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  11
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• METHODS OF SEPARATING FTC ISOMERS AND DERIVATIVES THEREOF
  申请人：Pharm-Eco Laboratories Inc.

  公开号：EP1180104A1

  公开（公告）日：2002-02-20
• US6541631B1
  申请人：——

  公开号：US6541631B1

  公开（公告）日：2003-04-01
• US6752929B1
  申请人：——

  公开号：US6752929B1

  公开（公告）日：2004-06-22
• [EN] METHODS OF SEPARATING FTC ISOMERS AND DERIVATIVES THEREOF<br/>[FR] PROCEDES DE SEPARATION D'ISOMERES FTC ET LEURS DERIVES
  申请人：PHARM ECO LAB INC

  公开号：WO2000071539A1

  公开（公告）日：2000-11-30

  The present invention relates to a method of preparing enantiomers and diastereomers of a 2', 3'-dideoxy-5-fluoro-3' thiocytadine (FTC) or a derivative thereof as represented by the structural formula (I), wherein R is H, a substituted or unsubstituted organic acid radical, a substituted or unsubstituted alkyl group, a substituted or unsubstituted aryl group, a substituted or unsubstituted heteroaryl group, a substituted or unsubstituted aralkyl group, a substituted or unsubstituted heteroarakyl group, a substitute or unsubstituted cycloalkyl group, a substituted or unsubstituted heterocycloalkyl group, a substituted or unsubstituted cycloalkylalkyl, a substituted or unsubstituted heterocycloalkylalkyl, a sugar or a protecting group.